PurposeThe credit of agricultural product quality and safety reflects the ability of the main actors involved in the supply chain to provide reliable agricultural products to consumers. To fundamentally solve the problem of agricultural product quality and safety, it is worth studying how to make the credit awareness and integrity self-discipline of the supply chain agriculture-related subjects strengthened and the role and value of credit supervision given full play. Starting from the application of blockchain in the agricultural product supply chain, this paper aims to investigate the main factors affecting the credit regulation of agricultural product quality.Design/methodology/approachUsing the DEMATEL-ISM (decision-making trial and evaluation laboratory–interpretative structural modeling) method, we analyze the credit influencing factors of agricultural quality and safety empowered by blockchain technology, find the causal relationship between the crucial influencing factors and deeply explore the hierarchical transmission relationship between the influencing factors. Then, the path analysis in structural equation modeling is utilized to verify and measure the significance and effect value of the transmission relationship among the crucial influencing factors of credit regulation.FindingsThe results show that the quality and safety credit regulation of agricultural products is influenced by a combination of direct and deep influencing factors. Long-term stable cooperative relationship, Quality and safety credit evaluation, Supply chain risk control ability, Quality and safety testing, Constraints of the smart contract are the main influence path of blockchain embedded in agricultural product supply chain quality and safety credit supervision.Originality/valueCredit supervision is an important means to improve the ability and level of social governance and standardize the market order. From the perspective of blockchain embedded in the agricultural supply chain, the regulatory body is transformed from the product body to the supply chain body. Take the credit supervision of supply chain subjects as the basis of agricultural product quality supervision. With the help of blockchain technology to improve the effectiveness of agricultural product quality and safety credit supervision, credit supervision is used to constrain and incentivize the behavior of agricultural subjects.