This experiment was undertaken to compare the effects of using the Enzymmix F product with a Brazilian enzyme blend in diets with different nutritional levels. A total of 1,080 male broiler chicks were distributed into a randomized-block design with a 3 × 2 factorial arrangement consisting of three enzyme complexes (Enzyme Blend, Enzymmix F, and the combination of both) and two nutritional levels (regular and reduced). We evaluated the birds' performance in the periods of 1 to 21 and 1 to 42 days of age. The yields of carcass and cuts and intestinal integrity were evaluated at 45 days of age. During the analyzed periods, no significant difference was observed for the performance parameters considering the "enzyme" factor. However, the reduction in the nutritional level of the diet resulted in inferior performance in both periods. There was no statistical difference for the yields (%) of carcass and cuts. Enzymmix F provided the greatest villus height in the jejunum segment. The use of the Enzyme Blend in the nutritionally reduced diet led to a lower crypt depth. In conclusion, Enzymmix F increased the weight of wings (g) and the villus height in the jejunum.