Contact dermatitis due to a massage liniment containing <i>Inula helenium</i> extract

Pazzaglia, Massimiliano; Venturo, Nicola; Borda, G; Tosti, Antonella

doi:10.1111/j.1600-0536.1995.tb00479.x

Cited by 24 publications

(13 citation statements)

References 5 publications

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“…36 Massage liniment has been reported to cause a contact dermatitis and could therefore potentially cause problems in men, although to date, this has not been described. 37 Exercise Exercise induced urticaria and anaphylaxis are well documented. 38 Symptoms may be intermittent and often require an additional factor, such as food sensitivity.…”

Section: Oral Medicationsmentioning

confidence: 99%

Genital allergy

Sonnex

2004

Sexually Transmitted Infections

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Section: Oral Medicationsmentioning

confidence: 99%

Genital allergy

Sonnex

2004

Sexually Transmitted Infections

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“…SLs are contained in the essential oil of milfoil, but due to its presumedly low water‐solubility it is not known whether the reaction to the tea was caused by small amounts of SLs or some other allergen such as, e.g., a flavonoid (6). Sensitization from a plant‐based massage liniment containing bay leaf and 3 Compositae species, including milfoil, was ascribed to elecampane without patch testing all constituents (13).…”

Section: Achillea Millefolium L(milfoil Yarrow; Inci Name Achillea mentioning

confidence: 99%

Contact sensitization from Compositae‐containing herbal remedies and cosmetics

Paulsen

2002

Contact Dermatitis

141

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The Compositae (Asteraceae) family of plants is currently an important cause of allergic plant contact dermatitis in Europe. The family comprises some of the oldest and most valued medicinal plants, and the increasing popularity of herbal medicine and cosmetics may theoretically result in a growing number of Compositae sensitizations from these sources. According to the literature at least 15 species, including among others arnica (Arnica montana), German and Roman chamomile (Chamomilla recutita and Chamaemelum nobile), marigold (Calendula officinalis), Echinacea and elecampane (Inula helenium), have been suspected of sensitization or elicitation of Compositae dermatitis. Epidemiological data are available for 2 species only, arnica and German chamomile, the rest of the evidence being anecdotal. Based on this, sensitization seems to occur relatively frequently with a few species such as arnica and elecampane, and occurs rarely with the majority, especially the widely used German chamomile. Sesquiterpene lactones are the most important allergens, but there are a few cases of sensitization from a coumarin, a sesquiterpene alcohol and a thiophene. The risk of elicitation of dermatitis by using Compositae-containing products in Compositae-sensitive individuals is by-and-large unknown.

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“…Many secondary metabolites have been identified, notably sesquiterpenes (Harborne and Baxter 1996). I. helenium extracts and constituents have been positively tested to fight mycobacteria (Cantrell et al 1999) and the trematode Clonorchis sinensis (Rhee et al 1999), but they might also cause contact dermatitis (Pazzaglia et al 1999). Protozoocidal and piscicidal activities have been reported from I. montana and I. nervosa, respectively (Martin et al 1998;Yoshida et al 1995).…”

Section: Discussionmentioning

confidence: 98%

Screening of medicinal and ornamental plants for insecticidal and growth regulating activity

Alexenizer

Dorn

2007

J Pest Sci

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Extracts of 121 medicinal and ornamental plants were screened for insecticidal and growth regulating activity to milkweed bug, Oncopeltus fasciatus Dallas. The most effective extracts stemmed from Inula helenium L., Rumex crispus L., R. acetosa L., Asarum europaeum L., and Calendula officinalis L. All these extracts exerted growth inhibiting activities and moderate or low acute toxicity. Most promising were extracts of dried roots of I. helenium. Besides a moderate chronic toxicity which reduced the fitness of the milkweed bug, the treatment produced overaged nymphs, supernumerary nymphs, disturbances of the moulting process, morphological defects, delay of adult maturation and reduction of fecundity. In addition, I. helenium extracts had a strong antifeedant effect when topically applied and very strong repellent effect when applied to the food (peeled sunflower kernels). It is obvious that the extract contains several active constituents. Such a cocktail may reduce the threat of rapid resistance development.

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Contact dermatitis due to a massage liniment containing Inula helenium extract

Cited by 24 publications

References 5 publications

Genital allergy

Genital allergy

Contact sensitization from Compositae‐containing herbal remedies and cosmetics

Screening of medicinal and ornamental plants for insecticidal and growth regulating activity

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