Contact dermatitis from glucose sensors in Spain: A multicentric approach

Abstract

Background Allergic contact dermatitis from glucose sensors may interfere with their ongoing application. Objective To evaluate a series of Spanish patients with contact dermatitis to glucose sensors regarding former sources of contact allergens, patch test results, and outcomes from the ongoing use of the device. Methods A series of patients with contact dermatitis from glucose sensors was investigated in eight dermatology departments across Spain (epidemiological features, brands, latency time to develop dermatitis, the ability to continue using the devices as well as the patch test results). Results Thirty patients were evaluated (mean age 20.9 years). A total of 66.7% were children and 66.7% female. Ninety per cent used Freestyle Libre (FSL). Eight of 26 (30.8%) reacted to isobornyl acrylate (IBOA) and two of 20 (10.0%) to N,N dimethylacrylamide (DMAA). The mean latency time to develop dermatitis was 9 months. Sixteen of 29 (55.2%) patients continued using the same sensor causing the reaction. Thirteen of 29 (44.8%) patients were unable to continue using the sensor because of severe reactions. Of these, five were positive to IBOA, one to IBOA and DMAA, one to DMAA, one to colophony, and one to isopropyl alcohol wipes. In one patient, the outcome was unknown. Conclusion The frequency of sensitisation to IBOA and DMAA, was lower than in other European series, but similar to a previously published Spanish article. Legislation requiring manufacturers to provide information regarding the composition of medical devices and cooperate with the investigations into contact dermatitis is urgently needed.

Prognosis and sequelae of meth(acrylate) sensitization in beauticians and consumers of manicure materials

“…(Meth)acrylate sensitization costs are not exclusively limited to the ability to work as a nail technician or consume manicure materials. Several reports have already been published on patients who acquired ACDMA in manicure products and subsequently developed reactions from dental materials, 10–13 knee prostheses 14 or glucose sensors 15 …”

“…Several reports have already been published on patients who acquired ACDMA in manicure products and subsequently developed reactions from dental materials, [10][11][12][13] knee prostheses 14 or glucose sensors. 15 We describe the results of research on the prognosis and sequelae of ACDMA in manicure products involving patients diagnosed in two Spanish Dermatology Departments throughout the last few years.…”