CONTAMINATED PROBLEMATIC SKIN WOUNDS IN DIABETIC PATIENTS TREATED WITH AUTOLOGOUS PLATELET-RICH PLASMA (PRP): A case series study

Sokolov, Tsvetan; Валентинов, Б. Г.; Andonov, Jordan; Angelov, S; Kosev, Pencho

doi:10.5272/jimab.2016221.1067

JofIMAB

2016

DOI: 10.5272/jimab.2016221.1067

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CONTAMINATED PROBLEMATIC SKIN WOUNDS IN DIABETIC PATIENTS TREATED WITH AUTOLOGOUS PLATELET-RICH PLASMA (PRP): A case series study

Tsvetan Sokolov¹,

Б. Г. Валентинов²,

Jordan Andonov³

et al.

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Cited by 2 publications

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The Management of Postsurgical Wound Complications with Plasma Rich in Growth Factors: A Preliminary Series

Anitua

Pino

2020

Adv Skin Wound Care

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BACKGROUND Postsurgical wound complications constitute a relevant public health issue because of their frequency. There is growing evidence regarding platelet-based autologous therapies that support their use in promoting cutaneous regeneration. OBJECTIVE To provide preliminary data regarding the potential benefit of plasma rich in growth factors (PRGF) in the management of postsurgical wound complications. DESIGN Three patients suffering from poorly healing severe full-thickness wounds were treated with either one or a combination of different formulations derived from their own blood: autologous clot, fibrin membrane, injectable plasma, or topical ointment. Different treatment protocols are described, and follow-up results are reported. RESULTS Within 4 to 12 months, the treated wounds healed completely with no signs of infection, tissue necrosis, or functional impairment. No adverse events were reported. CONCLUSION Additional clinical trials with long-term follow-up periods and larger patient populations are needed to establish the efficacy of PRGF technology. However, these preliminary findings suggest that PRGF merits further randomized controlled studies exploring its capacity to accelerate re-epithelialization and restore functional integrity to cutaneous ulcers resulting from surgical complications.

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The Management of Postsurgical Wound Complications with Plasma Rich in Growth Factors: A Preliminary Series

Anitua

Pino

2020

Adv Skin Wound Care

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Biological Approach for Managing Severe Gunshot Wounds

Muñoz

Martínez

Echevarria

et al. 2018

Journal of Wound, Ostomy &Amp; Continence Nursing

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CONTAMINATED PROBLEMATIC SKIN WOUNDS IN DIABETIC PATIENTS TREATED WITH AUTOLOGOUS PLATELET-RICH PLASMA (PRP): A case series study

Cited by 2 publications

References 15 publications

The Management of Postsurgical Wound Complications with Plasma Rich in Growth Factors: A Preliminary Series

The Management of Postsurgical Wound Complications with Plasma Rich in Growth Factors: A Preliminary Series

Biological Approach for Managing Severe Gunshot Wounds

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