Aesthetic defects are a violation of quality attributes that are symptoms of bad interface design programming decisions. They lead to deteriorating the perceived usability of mobile user interfaces and negatively impact the Users eXperience (UX) with the mobile app. Most existing studies relied on a subjective evaluation of aesthetic defects depending on end-users feedback, which makes the manual evaluation of mobile user interfaces human-centric, time-consuming, and error-prone. Therefore, recent studies have dedicated their effort to focus on the definition of mathematical formulas that each targets a specific structural quality of the interface. As the UX is tightly dependent on the user profile, the combination and calibration of quality attributes, formulas, and users characteristics, when defining a defect, is not straightforward. In this context, we propose a fully automated framework which combines literature quality attributes with the users profile to identify aesthetic defects of MUI. More precisely, we consider the mobile user interface evaluation as a multi-objective optimization problem where the goal is to maximize the number of detected violations while minimizing the detection complexity of detection rules and enhancing the interfaces overall quality in means