Continuous Biocatalytic Processes

Rao, Nagaraj N.; Lütz, Stephan; Würges, Kerstin; Minör, D.

doi:10.1021/op800314f

Cited by 53 publications

(31 citation statements)

References 50 publications

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“…The packed-bed reactor (PBR) generally leads to higher performance than a continuous stirred-tank reactor. In addition, the volumes are reduced, the technology is less expensive (no mobile parts) and enzyme support attrition is avoided (Balcão et al, 1996;Rao et al, 2009).…”

Section: Introductionmentioning

confidence: 99%

Continuous lipase-catalyzed production of esters from crude high-oleic sunflower oil

Séverac

Galy

Turon³

et al. 2011

Bioresource Technology

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Section: Introductionmentioning

confidence: 99%

Continuous lipase-catalyzed production of esters from crude high-oleic sunflower oil

Séverac

Galy

Turon³

et al. 2011

Bioresource Technology

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“…Continuous processes are recognized to give benefits such as reduced down-times, increased space-time yields, steadystate operation, improved heat, and mass transfer control, to name a few [56][57][58]. However, not all processes are suited to be operated in continuous modes [21].…”

Section: A Microfluidic Toolbox For Ispr Developmentmentioning

confidence: 99%

A Microfluidic Toolbox for the Development of In-Situ Product Removal Strategies in Biocatalysis

Heintz¹,

Mitić²,

Ringborg³

et al. 2016

J Flow Chem

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A microfluidic toolbox for accelerated development of biocatalytic processes has great potential. This is especially the case for the development of advanced biocatalytic process concepts, where reactors and product separation methods are closely linked together to intensify the process performance, e.g., by the use of in-situ product removal (ISPR). This review provides a general overview of currently available tools in a microfluidic toolbox and how this toolbox can be applied to the development of advanced biocatalytic process concepts. Emphasis is placed on describing the possibilities and advantages of the microfluidic toolbox that are difficult to achieve with conventional batch-processbased technologies. Application of this microfluidic toolbox will potentially make it possible to intensify biocatalytic reactions and thereby facilitate the development towards novel and advanced biocatalytic processes, which in many cases have proven too difficult in conventional batch equipment.

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“…Although most examples involve batch processes, many different examples of continuous biocatalytic processes are known [62]. If we do not consider membrane reactors in detail, then packed-bed reactors represent the most common assembly used for polymersupported biocatalysts.…”

Section: Polymer-supported Biocatalystsmentioning

confidence: 99%