Continuous blood pressure measurement using the pulse transit time: Comparison to intra-arterial measurement

Abstract

Continuous blood pressure (BP) measurement allows the investigation of transient changes in BP and thus may give insights into mechanisms of BP control. We validated a continuous, non-invasive BP measurement based on the pulse transit time (PTT), i.e., BP(PTT), by comparing it with the intra-arterial BP (BP(i.a.)) measurement. Twelve subjects (five females and seven males) were included. BP(i.a.) was obtained from the radial artery using a system from ReCor Medical. Systolic and diastolic BP were calculated using the PTT (BP(PTT), SOMNOscreen). (PTT) was determined from the electrocardiogram and the peripheral pulse wave. The BP was modulated by application of increasing doses of dobutamine (5, 10, 20 μg/kg body mass). Systolic BP(PTT) and systolic BP(i.a.) correlated significantly (R = 0.94). The limits of agreement in the Bland-Altman plot were ± 19 mmHg; the mean values differed by 1 mmHg. The correlation coefficient for the diastolic BP measurements was R = 0.42. The limits of agreement in the Bland-Altman plot were ± 18 mmHg, with a mean difference of 5 mmHg in favour of the BP(PTT). The study demonstrates a significant correlation between the measurement methods for systolic BP. The results encourage the application of PTT-based BP measurement for the evaluation of BP dynamics and pathological BP changes.

Comparison between blood pressure during obstructive respiratory events in REM and NREM sleep using pulse transit time

“…Notably, a direct method based on the relationship between BP and the pulse wave velocity (PWV) can be used to determine BP noninvasively. Good correlations have been found between cardiovascular parameters and BP assessed using the pulse transit time (PTT) in patients with OSA 21 , and BP measured using the PTT is comparable with that assessed by reference methods [22][23][24][25] .…”

High‐Performance Flexible Tactile Sensor Enabling Intelligent Haptic Perception for a Soft Prosthetic Hand

“…So accurate waveform is essential to the quantitative analysis of the cardiovascular parameters. In addition, pulse transit time (PTT) has been demonstrated as one of the potential parameters for noninvasive estimation of the arterial viscoelastic properties and blood pressure, which could be obtained by the time interval between the characteristic points of electrocardiograph (ECG) and peripheral pressure pulse and takes only about 200 ms . So, even a small distortions in the pulse wave will affect the accuracy of PTT.…”

Kontinuierliche nicht-invasive Blutdruckmessung mittels Pulswellen-Transit-Zeit bei Kindern und Jugendlichen

“…Ein Vergleich der Messwerte mittels PTZ-Methode und der direkten intraarteriellen Messung zeigte für den systolischen Blutdruck eine gute Korrelation (r = 0,894), aber nicht für den diastolischen Blutdruck (r = 0,496). Ähnliche Korrelationen fanden sich bei Studien an Erwachsenen [2,18]. In der Studie von Patzak und Mitarbeiter lagen die Korrelation des systolischen Blutdrucks bei r = 0,94 und des diastolischen Drucks bei r = 0,42 und damit ähnlich zu unserer Studie [18].…”

“…Ähnliche Korrelationen fanden sich bei Studien an Erwachsenen [2,18]. In der Studie von Patzak und Mitarbeiter lagen die Korrelation des systolischen Blutdrucks bei r = 0,94 und des diastolischen Drucks bei r = 0,42 und damit ähnlich zu unserer Studie [18]. Insgesamt konnte auch in dieser Studie erstmals an Kindern wie bei Erwachsenen festgestellt werden, dass die PTZ-Methode den systolischen Blutdruck besser misst als den diastolischen Blutdruck [7,9,23].…”