Continuous Flow Synthesis of Group 11 Metal‐NHC Complexes [M(IPr)(OC(H)(CF₃)₂)] (with M=Cu, Ag and Au)

Abstract

The weak base method in continuous flow is one of the most sustainable and attractive approaches towards the synthesis of transition metal NHC complexes. Herein, we broaden the scope of this method by deploying it to synthesize [M(IPr)(OC(H)(CF3)2)] complexes, including copper, silver, and gold‐centered complexes. These compounds bear an alkoxide ligand which can create new opportunities in harnessing the unique properties of HFIP (1,1,1,3,3,3‐hexafluoroisopropanol) in catalysis.