2022
DOI: 10.5812/gct-128050
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Continuous Training and Crocin Supplementation Alleviates Doxorubicin-Induced Hepatocyte Apoptosis in Male Rats

Abstract: Background: Chemotherapy drugs can cause liver damage by causing hepatotoxicity. Objectives: This study aimed to determine the interactive effect of continuous training and Crocin supplementation on hepatocyte apoptosis in male rats induced by doxorubicin. Methods: In this experimental study, 40 Wistar rats were randomly assigned to: (1) Healthy, (2) doxorubicin (Dox), (3) Dox + crocin (Cr), (4) Dox + continuous training (CT), and (5) Dox + CT + Cr. Group 1 received normal saline daily; groups 2 to 5 received … Show more

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