Continuous-Wave THz Imaging for Biomedical Samples

Zhang, Yaya; Wang, Chuting; Huai, Bingxin; Wang, Shiyu; Zhang, Yating; Wang, Dayong; Rong, Lü; Zheng, Yongchang

doi:10.3390/app11010071

Cited by 58 publications

(28 citation statements)

References 93 publications

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“…The upper and lower wings of a butterfly reflect THz waves at f 1 and f 2 , respectively, so their spectral responses, i.e., colors, are different. To obtain the spectral information of the object, we used a continuous wave THz source 40 . The two THz beams with frequencies of f 1 and f 2 incident on the SLM subsequently can be spatially encoded by the SLM.…”

Section: Concept and Design Of Dual-color Thz Slmmentioning

confidence: 99%

Dual-color terahertz spatial light modulator for single-pixel imaging

et al. 2022

Light Sci Appl

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Spatial light modulators (SLM), capable of dynamically and spatially manipulating electromagnetic waves, have reshaped modern life in projection display and remote sensing. The progress of SLM will expedite next-generation communication and biomedical imaging in the terahertz (THz) range. However, most current THz SLMs are adapted from optical alternatives that still need improvement in terms of uniformity, speed, and bandwidth. Here, we designed, fabricated, and characterized an 8 × 8 THz SLM based on tunable liquid crystal metamaterial absorbers for THz single-pixel compressive imaging. We demonstrated dual-color compressive sensing (CS) imaging for dispersive objects utilizing the large frequency shift controlled by an external electric field. We developed auto-calibrated compressive sensing (ACS) algorithm to mitigate the impact of the spatially nonuniform THz incident beam and pixel modulation, which significantly improves the fidelity of reconstructed images. Furthermore, the complementary modulation at two absorption frequencies enables Hadamard masks with negative element values to be realized by frequency-switching, thereby halving the imaging time. The demonstrated imaging system paves a new route for THz single-pixel multispectral imaging with high reliability and low cost.

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Section: Concept and Design Of Dual-color Thz Slmmentioning

confidence: 99%

Dual-color terahertz spatial light modulator for single-pixel imaging

et al. 2022

Light Sci Appl

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“…During the years, THz spectroscopy proved to be a very useful and successful tool for the investigation of many processes in pharmaceuticals, biology, and bio-medicine, since it probes low frequency vibrational modes [126][127][128][129]. These vibrations define large scale conformational changes occurring along the torsional degrees of freedom in complex biopolymers [130][131][132].…”

Section: Molecular Dynamics Structural Biology and Bio-medical Applic...mentioning

confidence: 99%

Multi-Pass Free Electron Laser Assisted Spectral and Imaging Applications in the Terahertz/Far-IR Range Using the Future Superconducting Electron Source BriXSinO

et al. 2022

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Free-Electron Lasers are a rapidly growing field for advanced science and applications, and worldwide facilities for intense field generation, characterization and usage are becoming increasingly popular due to their peculiarities, including extremely bright, coherent, wide band tunable ultra-short pulses which are not achievable with other techniques up to now. In this review we give a thorough survey of the latest advances in the Free-Electron Laser-based field generation and detection methodologies and then present the main characteristics of a future THz/IR source, named TerRa@BriXSinO, based on a superconducting linear accelerator. The foreseen source is strongly monochromatic, with a bandwidth of 1% or smaller, highly coherent both transversally and longitudinally, with extreme versatility and high frequency tunability. After introducing the most recent and novel FEL-assisted scientific investigations, including fundamental explorations into complex systems and time-dependent interactions and material dynamics, we present our vision on the potential use of the TerRa facility and analyze some possible applications, ranging from non-linear physics under extreme conditions to polarization sensitive imaging and metamaterial-based sensing.

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“…The CW THz transmission imaging system is more suitable to map thin tissue samples with weak absorption of THz radiation. As shown in Figure 3 , the leaf sample is placed at the focal position of the incident beam and scanned pixel by pixel by moving it along the X–Y plane [ 60 ]. It is suitable for verifying the effectiveness of the CW THz transmission imaging system as the leaf can be considered as a 2D thin sample.…”

Section: Thz Imaging and Spectroscopymentioning

confidence: 99%

Terahertz Imaging for Breast Cancer Detection

Wang

2021

Sensors

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Terahertz (THz) imaging has the potential to detect breast tumors during breast-conserving surgery accurately. Over the past decade, many research groups have extensively studied THz imaging and spectroscopy techniques for identifying breast tumors. This manuscript presents the recent development of THz imaging techniques for breast cancer detection. The dielectric properties of breast tissues in the THz range, THz imaging and spectroscopy systems, THz radiation sources, and THz breast imaging studies are discussed. In addition, numerous chemometrics methods applied to improve THz image resolution and data collection processing are summarized. Finally, challenges and future research directions of THz breast imaging are presented.

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Continuous-Wave THz Imaging for Biomedical Samples

Cited by 58 publications

References 93 publications

Dual-color terahertz spatial light modulator for single-pixel imaging

Dual-color terahertz spatial light modulator for single-pixel imaging

Multi-Pass Free Electron Laser Assisted Spectral and Imaging Applications in the Terahertz/Far-IR Range Using the Future Superconducting Electron Source BriXSinO

Terahertz Imaging for Breast Cancer Detection

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