The Eastern High Atlas (Morocco) contains a variety of rocks with different magnetic susceptibility, among these rocks are those which constitute the Proterozoic and Paleozoic basement of the plain of Tamlelt which is the study area. This work is devoted to the analysis and interpretation of the main magnetic anomalies using the Oisis Montaj program, and the correlation using ArcGis software, from the main « magnetic facies» detected, to the main geological formations affecting the geological basement, highlighted in the plain of Tamlelt. The map of the residual magnetic field shows elongated magnetic anomalies in the direction E-W and NE-SW. the reduction to the pole shows at the level of the plain of Tamlelt a large anomaly elongated in the direction E-W then in the direction NW-SE. The transformation of Tilt Angle allowed to delimit the anomalies of low or high amplitude that limit the shallow structures. The quantitative interpretation of the main magnetic anomalies highlighted in the study area has made it possible to characterize the deep structure of the magnetic bodies, which could contain sulphide clusters, according to the geological and mining context of the studied area.