Contribution to the study of physiology and pathophysiology of sleep in healthy individual and patients suffering from major depression and primary insomnia

Hein, Matthieu; Lanquart, JP; Loas, G; Hubain, Philippe; Linkowski, Paul

doi:10.30637/2019.19-057

Rev Med Brux

2020

DOI: 10.30637/2019.19-057

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Contribution to the study of physiology and pathophysiology of sleep in healthy individual and patients suffering from major depression and primary insomnia

Matthieu Hein¹,

JP Lanquart²,

G Loas³

et al.

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2024

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Cited by 1 publication

References 44 publications

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Risk of Comorbid Insomnia Disorder Associated with Major Depression in Apneic Patients: A Cross-Sectional Study

Hein,

Wacquier,

Conenna

et al. 2024

Clocks & Sleep

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Given the limitations of available studies, the objective of this study was to explore the role played by current and remitted major depression in the occurrence of comorbid insomnia disorder for apneic patients. Data from 1488 apneic patients were extracted from the medical reports of polysomnographic recordings available in the database of the Sleep Laboratory. The presence of comorbid insomnia disorder in these apneic patients was defined based on the diagnostic criteria of the American Academy of Sleep Medicine Work Group. The risk of comorbid insomnia disorder associated with current or remitted major depression in apneic patients was investigated using multivariate logistic regression models. After adjustment for the main confounding factors, multivariate logistic regression analyses revealed that remitted and current major depression were significantly associated with the occurrence of comorbid insomnia disorder in apneic patients. The findings of this study seem to indicate that comorbid insomnia disorder could be a residual symptom and a marker of major depression in apneic patients, which justifies the establishment of an adequate treatment for major depressive episodes and their potential residual symptoms to allow the better management of comorbid insomnia disorder and the better prevention of its potential negative consequences in this particular subpopulation.

show abstract

Risk of Comorbid Insomnia Disorder Associated with Major Depression in Apneic Patients: A Cross-Sectional Study

Hein,

Wacquier,

Conenna

et al. 2024

Clocks & Sleep

View full text Add to dashboard Cite

show abstract

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Contribution to the study of physiology and pathophysiology of sleep in healthy individual and patients suffering from major depression and primary insomnia

Cited by 1 publication

References 44 publications

Risk of Comorbid Insomnia Disorder Associated with Major Depression in Apneic Patients: A Cross-Sectional Study

Risk of Comorbid Insomnia Disorder Associated with Major Depression in Apneic Patients: A Cross-Sectional Study

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