Control Design for Dengue Fever Model with Disturbance

Abstract

A mathematical model has become a useful tool to predict and control dengue fever dynamics. In reality, the dynamic of dengue fever transmission can be disturbed by uncertainty measurements, so it is needed to consider the disturbance in the model. Then, dengue fever model with disturbance is constructed by using a gain matrix consisting a covariance matrix and random vector. As dengue vaccine has been challenging to reduce the pandemic, a dengue model with vaccination as control is constructed. The aim is to propose a feedback controller that can reduces the infected human (H2 control problem) and the uncertainty measurements (H∞ control problem). The control u denotes the proportion of susceptible humans that one decides to vaccinate at time t. A random mass vaccination with wanning immunity is chosen because vaccine still on development process. A Design of mixed H2 - H∞ control with State-dependent Riccati Equation (SDRE) approach is applied. The SDRE has been an effective method to solve for synthesizing nonlinear feedback controller by transforming the system to an State-dependent coefficient (SDC) form. By comparing the mixed scheme with basic H∞, numerical simulation shows that the control application effectively decreases the number of infected humans and reduces the disturbance.