The bioeconomic strategy of Ukraine has not been yet formed, the development of biotechnology is slow, the use of biotechnology is still very fragmentary. The main economic biotechnology sectors of Ukraine are agriculture, pharmaceuticals, food industry and bioenergy. A circular, sustainable bio-economy can become the primary tool for Ukraine’s integration into the EU Green Economy, making its economy more sustainable and competitive. The article aims to develop scientific and methodical aspects of the bioeconomic transformation of the national economy of Ukraine. The paper conducts a comprehensive assessment of the bioeconomic potential of the agri-food sector of the Ukrainian economy and identifies the main development priorities. The dynamics of alternative energy consumption and production from alternative energy sources have been provided.