Controlled fabrication of Au@MnO2 core/shell assembled nanosheets by localized surface plasmon resonance

Gao, Mengwei; Song, Yuanbo; Liu, Yidan; Jiang, Wentao; Peng, Jianchao; Shi, Liyi; Jia, Rongrong; Muhammad, Yaseen; Huang, Lei

doi:10.1016/j.apsusc.2020.147912

Cited by 23 publications

(11 citation statements)

References 60 publications

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“…High-resolution Mn 2p, Mn 3s, and O 1s spectra (Figure S9) indicated that Mn mainly existed in the form of Mn 4+ (MnO 2 ), minor Mn 3+ , , and unreacted Mn 2+ in RKCM , along with covalent bonds, such as O–H, Mn–OH, and Mn–O–Mn . The UV–vis absorption spectra of RKCM (Figure S10) showed a Ce6 Soret band at 402 nm and a red-shifted Ce6 Q band at 665 nm. , Compared with RKC , RKCM exhibited a blue shift and a shape change at 402 nm peak (Figure S7), which may relate to the surface plasmon resonance effect of MnO 2 . The loading ratio of Ce6 in RKCM was up to 73% as measured by the standard curve method (Figure S11), demonstrating the high loading efficiency of Ce6 in RK fibrils.…”

Section: Resultsmentioning

confidence: 97%

Cancer-Responsive Multifunctional Nanoplatform Based on Peptide Self-Assembly for Highly Efficient Combined Cancer Therapy by Alleviating Hypoxia and Improving the Immunosuppressive Microenvironment

Liu

Cao

et al. 2023

ACS Appl. Mater. Interfaces

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Hypoxia, as a main feature of the tumor microenvironment, has greatly limited the efficacy of photodynamic therapy (PDT), as well as its clinical application. Here, a multifunctional composite nanoplatform, the peptide/Ce6/MnO2 nanocomposite (RKCM), has been constructed to alleviate tumor hypoxia and increase the efficacy of PDT using rationally designed peptide fibrils to encapsulate chlorin e6 (Ce6) inside and to mineralize MnO2 nanoparticles on the surface. As a result, RKCM significantly improved the PDT efficacy by increasing reactive oxygen species (ROS) generation, decreasing tumor cell viability, and inhibiting tumor growth and metastasis. Besides, decreased HIF-1α expression and increased immune-activated cell infiltration were also observed in RKCM/laser treatment xenograft. Mechanically, (1) Ce6 can induce singlet oxygen (1O2) generation under laser irradiation to give photodynamic therapy (PDT); (2) MnO2 can react with H2O2 in situ to supply additional O2 to alleviate tumor hypoxia; and (3) the released Mn2+ ions can induce a Fenton-like reaction to generate •OH for chemical dynamic therapy (CDT). Moreover, RKCM/laser treatment also presented with an abscopal effect to block the occurrence of lung metastasis by remolding the pre-metastasis immune microenvironment. With these several aspects working together, the peptide/Ce6/MnO2 nanoplatform can achieve highly efficient tumor therapy. Such a strategy based on peptide self-assembly provides a promising way to rationally design a cancer-responsive multifunctional nanoplatform for highly efficient combined cancer therapy by alleviating hypoxia and improving the immune microenvironment.

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Section: Resultsmentioning

confidence: 97%

Cancer-Responsive Multifunctional Nanoplatform Based on Peptide Self-Assembly for Highly Efficient Combined Cancer Therapy by Alleviating Hypoxia and Improving the Immunosuppressive Microenvironment

Liu

Cao

et al. 2023

ACS Appl. Mater. Interfaces

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“…The high-resolution TEM image in Figure 2b presents the structure, where one may measure an interatomic distance of 2.3 Å (see zoom-in in Figure 2c), which is quite close to the interatomic distance in Au(111). 30 On the other hand, the overlayer has no different interlayer distance having an amorphous structure, which may be a result of the deposition procedure. The observation of this overlayer is indicative of effective coverage of the Au nanoparticles by the oxide.…”

Section: Resultsmentioning

confidence: 99%

Synthesis and Characterization of Au@MnO2 Nanoparticles as Plasmon Enhanced Spectroscopy Substrates

Oliveira¹,

Neves²,

Peixoto³

et al. 2023

J. Braz. Chem. Soc.

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The plasmonic properties of Au nanoparticles (AuNP), which allow the observation of enhanced spectroscopic effects, are strongly affected by the aggregation and precipitation caused by the strong interactions between nanoparticles. To avoid AuNP aggregation and precipitation, the present study proposes coating with MnO2, forming AuNP@MnO2 core-shell structures. The MnO2 layers presented 1-10 nm thickness so that highly surface-enhanced fluorescence was obtained with maximum intensity given by 5 nm thick MnO2. The decrease in Raman intensity could be controlled, despite the inherent reduction in surface-enhanced Raman scattering (SERS) intensity with increasing adsorbate-surface distance. The decrease in Raman intensity was compensated by increasing AuNP stability caused by the MnO2 shell.

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“…Synthesis of Au NPs. Au NPs were synthesized as follows [ 39 ]. First, sodium citrate solution (1 mL of 1% ( w / v )) was added to a micro-boiling HAuCl 4 solution (100 mL of 0.01% ( w / v )), and was maintained for a few minutes in this state.…”

Section: Methodsmentioning

confidence: 99%

Nanoenzyme Reactor-Based Oxidation-Induced Reaction for Quantitative SERS Analysis of Food Antiseptics

et al. 2022

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Nanoenzyme reactors based on shell-isolated colloidal plasmonic nanomaterials are well-established and widely applied in catalysis and surface-enhanced Raman scattering (SERS) sensing. In this study, a “double wing with one body” strategy was developed to establish a reduced food antiseptic sensing method using shell-isolated colloidal plasmonic nanomaterials. Gold nano particles (Au NPs) were used to synthesize the colloidal plasmonic nanomaterials, which was achieved by attaching ferrous ions (Fe2+), ferric ions (Fe3+), nitroso (NO−) group, cyanogen (CN−) group, and dopamine (DA) via coordinative interactions. The oxidation-induced reaction was utilized to generate •OH following the Fe2+-mediated Fenton reaction with the shell-isolated colloidal plasmonic nanomaterials. The •OH generated in the cascade reactor had a high oxidative capacity toward acid preservatives. Importantly, with the introduction of the signal molecule DA, the cascade reactor exhibited also induced a Raman signal change by reaction with the oxidation product (malondialdehyde) which improved the sensitivity of the analysis. In addition, the stable shell-isolated structure was effective in realizing a reproducible and quantitative SERS analysis method, which overcomes previous limitations and could extend the use of nanoenzymes to various complex sensing applications.

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Controlled fabrication of Au@MnO2 core/shell assembled nanosheets by localized surface plasmon resonance

Cited by 23 publications

References 60 publications

Cancer-Responsive Multifunctional Nanoplatform Based on Peptide Self-Assembly for Highly Efficient Combined Cancer Therapy by Alleviating Hypoxia and Improving the Immunosuppressive Microenvironment

Cancer-Responsive Multifunctional Nanoplatform Based on Peptide Self-Assembly for Highly Efficient Combined Cancer Therapy by Alleviating Hypoxia and Improving the Immunosuppressive Microenvironment

Synthesis and Characterization of Au@MnO2 Nanoparticles as Plasmon Enhanced Spectroscopy Substrates

Nanoenzyme Reactor-Based Oxidation-Induced Reaction for Quantitative SERS Analysis of Food Antiseptics

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