Convenient Heme Nanorod Modified Electrode for Quercetin Sensing by Two Common Electrochemical Methods

Abstract

Quercetin (Qu) is one of the most abundant flavonoids in the human diet. High concentrations of Qu can easily cause adverse effects and induce inflammation, joint pain and stiffness. In this study, Heme was used as a sensitive element and deposited and formed nanorods on a glassy carbon electrode (GCE) for the detection of Qu. The Heme/GCE sensor was characterized using scanning electron microscopy (SEM), cyclic voltammetry (CV), differential pulse voltammetry (DPV) and electrochemical impedance spectroscopy (EIS) techniques. Under optimized conditions, the developed sensor presented a linear concentration ranging from 0.1 to 700 μmol·L−1 according to the CV and DPV methods. The detection limit for the sensor was 0.134 μmol·L−1 and its sensitivity was 0.12 μA·μM−1·cm−2, which were obtained from CV analysis. Through DPV analysis we obtained a detection limit of 0.063 μmol·L−1 and a sensitivity of 0.09 μA·μM−1·cm−2. Finally, this sensor was used to detect the Qu concentration in loquat leaf powder extract, with recovery between 98.55–102.89% and total R.S.D. lower than 3.70%. The constructed electrochemical sensor showed good anti-interference, repeatability and stability, indicating that it is also usable for the rapid detection of Qu in actual samples.

Synergistic Amplification Signal Based on CoNPs and Melamine for Simultaneous Quantification of Epinephrine and Serotonin

“…Both techniques have been used extensively to monitor surface modifications, 24,25 and to assess surface. 26 Figure 2 shows the SEM and the corresponding EDS images of bare SPCE, CoNPs/ SPCE, and MEL/CoNPs/SPCE.…”

A new sensing platform based on a ternary nanocomposite of graphitic carbon nitride–silver sulfide–nickel molybdate for quercetin determination

“…1,2 The antioxidant properties of Que allow it to remove active oxygen, hydroxyl radicals, and superoxide anions very effectively. 5 In recent years, Que has been reported to be used as a potential inhibitor of flavin, a widely used antioxidant polyphenol with activity against RNA-dependent RNA polymerase of SARS-CoV-2. It has also been reported that Que enhances physical and mental performance.…”