Conventional stepwise vs. vital capacity rapid inhalation induction at two concentrations of sevoflurane

Martín-Larrauri, R.; Gilsanz, F.; Rodrigo, Juan P.; Vila, P.; Ledesma, M.; Casimiro, C.

doi:10.1097/00003643-200404000-00003

Cited by 13 publications

(2 citation statements)

References 29 publications

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“…Various studies are available with different anesthetic techniques and modalities, as for example, a multicenter study compared sevoflurane induction in three groups including conventional stepwise inhalation induction, vital capacity rapid inhalation induction at 4.5% & 8% sevoflurane. The time to loss of eyelash reflex was significantly less in 8% sevoflurane versus 4.5% sevoflurane 10 . Similar results were found in our study,the mean time to loss eyelashes reflex in 4.5% sevoflurane group was 88.5±6.71 sec and in 8% sevoflurane group the mean time to loss eyelashes reflex was 67.87±5.90 sec with p-value < 0.001.Addition of another inhalational anesthetic agent speeds up the time of induction as reported by El-Radaideh KM et al 11 who used 8% sevoflurane in 66% nitrous oxide and oxygen at 9 L/min the induction time was 51±4s.…”

Section: Discussionmentioning

confidence: 80%

Comparison of 4.5% Versus 8% Sevoflurane for Inhalational Induction in Adults

Sardar¹,

Azam²,

Bashir³

et al. 2023

PJMHS

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Background: Inhalational induction is a frequently used anesthetic technique in pediatric patients. However, it is less frequently used in adult patients undergoing surgery. General anesthesia can be induced either by intravenous injection or inhalation of anesthetic drugs. There are no established guidelines about the usage of 4.5% vs 8% sevoflurane for inhalation induction in adults undergoing elective day care surgery. Aim: To compare mean time to loss of eyelash reflex using 4.5% vs 8% sevoflurane for inhalational induction in adult patients undergoing elective day care surgery. Methodology: This randomized controlled trial was conducted in the department of anesthesia, Mayo Hospital Lahoreover a period of six months from June 2018 to December 2018. A total of 60 patients were enrolled in the study. We included adult patients aged 18-60 years of either gender and ASA status I & II undergoing elective day care surgery. While, patients having history of adverse reaction to inhalational agents and those who were on chronic sedatives, antipsychotic treatment were excluded. Demographic data of age and gender were obtained along with their body weight, height and BMI. They were randomly divided into two study groups using lottery method. After routine pre-op check and attaching standard anesthesia monitoring, patients in group-A and group-B were given 4.5% sevoflurane & 8% sevoflurane respectively at a fresh gas flow of 8 L/min of oxygen and they were instructed to take deep breaths while inhaling gas with help of face mask. Results: The mean age in 4.5% sevoflurane group was 42.27±11.83 years while in 8% sevoflurane group it was 45.43±12.76 years. In 4.5% sevoflurane group there were 12(40%) male and 18(60%) female cases while in 8% sevoflurane group there were 11(36.67%) male and 19(63.33%) female cases. The mean time to loss of eyelash reflex in 4.5% sevoflurane group was 88.57±6.71 seconds and in 8% sevoflurane group the mean time to loss eyelashes reflex was 67.87±5.90 seconds. The mean time to loss eyelashes reflex was statistically less in 8% sevoflurane group, with p-value 0.001. Conclusion: We concluded that mean time to loss eyelashes reflex was considerably lesser with8% sevoflurane when compared with 4.5% sevoflurane for inhalational induction in adult patients for elective day care surgery. Keywords: Inhalational induction, sevoflurane, eyelash reflex, day care surgery.

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Section: Discussionmentioning

confidence: 80%

Comparison of 4.5% Versus 8% Sevoflurane for Inhalational Induction in Adults

Sardar¹,

Azam²,

Bashir³

et al. 2023

PJMHS

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“…15 In clinical practise, the time difference is not of much importance as loss of consciousness (absent verbal response) may not mean optimum intubating conditions.…”

Section: Discussionmentioning

confidence: 99%

A comparative study of sevoflurane induction using continuous tidal volume breaths versus three vital capacity breaths technique in adult patients undergoing elective surgical procedures under general anaesthesia

Manik¹,

Dhama²,

Subhash³

et al. 2020

IJCA

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Introduction: Previous studies have shown stable cardiovascular parameters and minimal airway irritation with sevoflurane induction in adults. Also, time taken for induction is comparable to intravenous drugs. The authors planned to conduct a randomized, control study to compare the effect of continuous tidal volume breaths versus three vital capacity breaths for sevoflurane induction on time taken for induction, haemodynamic parameters and intubating conditions in adult patients undergoing elective surgery under general anaesthesia. Materials and Methods: Sixty patients planned to undergo elective surgical procedures under general anaesthesia were included in study. Patients were divided randomly using sealed opaque envelope method in group 1 and group 2 of thirty patients each. Group 1 patients received continuous tidal volume breath and group 2 patients received three vital capacity breaths. The statistical analysis was done using IBM SPSS Statistics Software Version 15.0. The independent samples Student t-test was used to determine the differences in basic clinical characteristics, mean Arterial Pressure, heart Rate, and intubation time between the two groups. Quantitative data were evaluated by chi square test. Any p value less than 0.05 was considered as significant. Result: Variation in heart rate between two groups was statistically significant at 1 min. (p=0.04), 2 min. (p=0.01) and 3 min. (p=0.004) after start of induction. The time taken for loss of consciousness was significantly less in vital capacity induction group. (p <0.001) Intubating conditions were better in group2 (optimal, good in 90% and 10% participants respectively) as compared to group1 (optimal, good in 76.67% and 23.33% participants respectively). Conclusion: Heart rate and mean arterial pressure remain stable during sevoflurane induction in adult patients using three vital capacity breath or tidal volume breath technique. Intubating conditions are better and time taken to lose consciousness is less with vital capacity breaths.

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High concentration versus low concentration sevoflurane for anaesthesia induction

Boonmak

Krisanaprakornkit

et al. 2007

Cochrane Database of Systematic Reviews

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Conventional stepwise vs. vital capacity rapid inhalation induction at two concentrations of sevoflurane

Cited by 13 publications

References 29 publications

Comparison of 4.5% Versus 8% Sevoflurane for Inhalational Induction in Adults

Comparison of 4.5% Versus 8% Sevoflurane for Inhalational Induction in Adults

A comparative study of sevoflurane induction using continuous tidal volume breaths versus three vital capacity breaths technique in adult patients undergoing elective surgical procedures under general anaesthesia

High concentration versus low concentration sevoflurane for anaesthesia induction

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