“…A recent systematic review and meta-analysis on 12 studies using Perceval Sutureless valve, Medtronic 3F Enable, or EDWARDS INTUITY confirmed that sutureless aortic valve implantation is a safe procedure associated with shorter cross-clamp and cardiopulmonary bypass time compared to conventional approaches 21. Sutureless and rapid deployment aortic valve replacement, furthermore, was associated with lower 30-day mortality and lower risk of postoperative aortic regurgitation compared to transapical TAVI in a multicenter, propensity-matched analysis22 and improved survival up to 24 months23 compared to TAVI, respectively. Compared to the implantation of stented valves, the use of Perceval sutureless valve in retrospective analyses resulted in shorter procedural times24 associated with better clinical outcomes as measured by blood transfusions, shorter intensive care unit stay, ventilation time, postoperative atrial fibrillation, pleural effusions, respectively, and reduced hospital costs by approximately 25% 25…”