Conversations About Alcohol Use in Pregnancy

Potential Link Between Exercise and N-Methyl-D-Aspartate Glutamate Receptors in Alcohol Use Disorder: Implications for Therapeutic Strategies

“…From a neurobiological standpoint, alcohol’s mechanism of action is complex and involves a plethora of neurotransmitters including dopamine (DA), where even the anticipation of alcohol consumption is enough to illicit neurotransmitter signaling effects. 23–28 Other neurotransmitters involved in alcohol consumption include glutamate, 29–39 and γ -aminobutyric acid (GABA), 26 , 27 , 40–43 as well as glycine receptors (GlyRs), 44 , 45 serotonin 46–48 and the peptide hormone vasopressin. 49 , 50 It is well-known that opioidergic mechanisms are also linked to ethanol neurochemical induced neurological insults.…”