As the drought becomes more and more serious, the distribution of general water and hydropower deserves more and more attention. We establish a multi-objective programming model based on the relationship between supply and demand to manage water usage and electricity generation at the Glen Canyon and Hoover dams to address these competing interests. Finally, the distribution of regional water rights is CA (42%), CO (24%), AZ (23%), NM (7%), WY (5%) respectively. The suitable allocation of water to agriculture, industry and residences is 7.05%, 66.56%, 26.39%. In addition, the model is solved according to sufficient and insufficient conditions. In the case of sufficient conditions, the time required to meet the total daily water demand of Lake Powell is 17.848 hours, the operation period is 221.22 days, and the water delivery to Mexico is 3.38maf. The time is 14.375 hours and the delivery of water to Mexico 1.354maf.