Copper-catalyzed oxidative dehydrogenative [3 + 2] annulation of oximes with α-amino ketones: entry to 3-aminopyrroles

Abstract

An unprecedented copper-catalyzed oxidative dehydrogenative [3 + 2] annulation of O-acyl oximes containing α-C(sp3)-H bonds with α-amino ketones for the preparation of 3-aminopyrroles is developed. This method handles O-acyl oximes...