Copper(I) and silver(I) coordination assemblies of imino-pyridyl and azino-pyridyl ligands: Syntheses, crystal structures, spectroscopic and photophysical properties

Mukherjee, Anindita; Dutta, Amal; Jana, Atish Dipankar; Patra, Goutam Kumar

doi:10.1016/j.ica.2013.04.012

Cited by 17 publications

(2 citation statements)

References 63 publications

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“…The Schiff bases are known for their fluorescence properties and their varied applications. 56 Therefore, we studied the luminescence properties of the obtained compounds and layers.…”

Section: Fluorescence Properties Of the Layersmentioning

confidence: 99%

Structural studies of copper(ii) complexes with 2-(2-aminoethyl)pyridine derived Schiff bases and application as precursors of thin organic–inorganic layers

et al. 2014

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Cu(ii) complexes with Schiff bases derived from 2-pyridin-2-ylethanamine were obtained and characterized by UV-Vis, fluorescence, and IR spectra. The X-ray crystal structures determined for [Cu(ii)(epy(di-t-Buba))Cl] × 0.042H2O and [Cu(ii)(epy(di-t-Buba))O2CCH3] revealed tetrahedral distortion of the Cu(ii) coordination sphere in the solid phase. For both molecules the Cu(ii) ions were found in tetragonal environments, as was confirmed by the values of EPR g-matrix diagonal components. The thermal properties of the complexes and the gas phase composition were studied by TG/IR techniques. Thin layers of the studied copper(ii) complexes were deposited on Si(111) by a spin coating method and characterized by scanning electron microscopy (SEM/EDS), atomic force microscopy (AFM) and fluorescence spectra. For copper(ii) layers the most intensive fluorescence band from intra-ligand transition was observed between 498 and 588 nm. The layers' fluorescence intensity was related to the rotation speed and deposition time.

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“…The Schiff bases are known for their fluorescence properties and their varied applications. 56 Therefore, we studied the luminescence properties of the obtained compounds and layers.…”

Section: Fluorescence Properties Of the Layersmentioning

confidence: 99%

Structural studies of copper(ii) complexes with 2-(2-aminoethyl)pyridine derived Schiff bases and application as precursors of thin organic–inorganic layers

et al. 2014

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“…As an organic helical molecule with a long history (De et al, 2006;Fisher & Stoufer, 1966), benzil dihydrazone (BDH) is often used to construct polydentate diazine Schiff bases (Tan et al, 2015), helical coordination complexes (Bai et al, 2012;Drew et al, 2007;Mukherjee et al, 2013) and, more importantly, a leading scaffold for the further design and synthesis of potential anticancer agents (Ke et al, 2013). Here we aimed to use the BDH scaffold to construct some novel Schiff bases, especially those containing indole rings.…”

Section: Introductionmentioning

confidence: 99%

Synthesis, crystal structures, antiproliferative activities and reverse docking studies of eight novel Schiff bases derived from benzil

et al. 2020

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Eight novel Schiff bases derived from benzil dihydrazone (BDH) or benzil monohydrazone (BMH) and four fused-ring carbonyl compounds (3-formylindole, FI; 3-acetylindole, AI; 3-formyl-1-methylindole, MFI; 1-formylnaphthalene, FN) were synthesized and characterized by elemental analysis, ESI–QTOF–MS, 1H and 13C NMR spectroscopy, as well as single-crystal X-ray diffraction. They are (1Z,2Z)-1,2-bis{(E)-[(1H-indol-3-yl)methylidene]hydrazinylidene}-1,2-diphenylethane (BDHFI), C32H24N6, (1Z,2Z)-1,2-bis{(E)-[1-(1H-indol-3-yl)ethylidene]hydrazinylidene}-1,2-diphenylethane (BDHAI), C34H28N6, (1Z,2Z)-1,2-bis{(E)-[(1-methyl-1H-indol-3-yl)methylidene]hydrazinylidene}-1,2-diphenylethane (BMHMFI) acetonitrile hemisolvate, C34H28N6·0.5CH3CN, (1Z,2Z)-1,2-bis{(E)-[(naphthalen-1-yl)methylidene]hydrazinylidene}-1,2-diphenylethane (BDHFN), C36H26N4, (Z)-2-{(E)-[(1H-indol-3-yl)methylidene]hydrazinylidene}-1,2-diphenylethanone (BMHFI), C23H17N3O, (Z)-2-{(E)-[1-(1H-indol-3-yl)ethylidene]hydrazinylidene}-1,2-diphenylethanone (BMHAI), C24H19N3O, (Z)-2-{(E)-[(1-methyl-1H-indol-3-yl)methylidene]hydrazinylidene}-1,2-diphenylethanone (BMHMFI), C24H19N3O, and (Z)-2-{(E)-[(naphthalen-1-yl)methylidene]hydrazinylidene}-1,2-diphenylethanone (BMHFN) C25H18N2O. Moreover, the in vitro cytotoxicity of the eight title compounds was evaluated against two tumour cell lines (A549 human lung cancer and 4T1 mouse breast cancer) and two normal cell lines (MRC-5 normal lung cells and NIH 3T3 fibroblasts) by MTT assay. The results indicate that four (BDHMFI, BDHFN, BMHMFI and BMHFN) are inactive and the other four (BDHFI, BDHAI, BMHFI and BMHAI) show severe toxicities against human A549 and mouse 4T1 cells, similar to the standard cisplatin. All the compounds exhibited weaker cytotoxicity against normal cells than cancer cells. The Swiss Target Prediction web server was applied for the prediction of protein targets. After analyzing the differences in frequency hits between these active and inactive Schiff bases, 18 probable targets were selected for reverse docking with the Surflex-dock function in SYBYL-X 2.0 software. Three target proteins, i.e. human ether-á-go-go-related (hERG) potassium channel, the inhibitor of apoptosis protein 3 and serine/threonine-protein kinase PIM1, were chosen as the targets. Finally, the ligand-based structure–activity relationships were analyzed based on the putative protein target (hERG) docking results, which will be used to design and synthesize novel hERG ion channel inhibitors.

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Structural Diversity in Manganese(II) Complexes with Multidentate N‐Donor Imino Pyridyl Ligands

Masoumi¹,

Gargari²,

Mahmoudi³

et al. 2015

Zeitschrift anorg allge chemie

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Four Mn(NCS)2 based compounds of the types [Mn(SCN)2(L1)]·EtOH (1), [Mn(SCN)2(L2)]·½EtOH (2), [Mn(SCN)2(L3)] (3), and [Mn(SCN)2(L4)2]n·3nMeCN (4) [L1 = benzilbis((pyridin‐2‐yl)methylidenehydrazone), L2 = benzilbis((acetylpyridin‐2‐yl)methylidenehydrazone, L3 = benzilbis((phenylpyridin‐2‐yl)methylidenehydrazone, and L4 = benzilbis((pyridin‐3‐yl)methylidenehydrazone)] were synthesized and characterized by single‐crystal X‐ray diffraction studies, elemental analysis, and IR spectroscopy. The first three complexes of general formula Mn(SCN)2(L1–3) consist of discrete units, whereas the fourth one consists of one‐dimensional coordination polymer. The central metal atoms in 1–4 exhibit a distorted octahedral arrangement.

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Copper(I) and silver(I) coordination assemblies of imino-pyridyl and azino-pyridyl ligands: Syntheses, crystal structures, spectroscopic and photophysical properties

Cited by 17 publications

References 63 publications

Structural studies of copper(ii) complexes with 2-(2-aminoethyl)pyridine derived Schiff bases and application as precursors of thin organic–inorganic layers

Structural studies of copper(ii) complexes with 2-(2-aminoethyl)pyridine derived Schiff bases and application as precursors of thin organic–inorganic layers

Synthesis, crystal structures, antiproliferative activities and reverse docking studies of eight novel Schiff bases derived from benzil

Structural Diversity in Manganese(II) Complexes with Multidentate N‐Donor Imino Pyridyl Ligands

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