Copper Oxide NPs: Synthesis and their Anti-Dermatophyte Activity against Trichophyton rubrum

Abstract

Trichophyton rubrum (T.rubrum) is a pathogenic dermatophyte that can causes fungal infection in keratinized layer of the human tissues such as skin, hair and nails. This work was carried out to study the antifungal activity of CuO nanoparticles (CuO NPs) on the viability of T.rubrum. CuO NPs have been synthesized by pulsed laser ablation of copper target immersed in liquid media using Q-switched pulsed Nd:YAG laser with 1064 nm. The optical properties and the surface charge of CuO NPs colloidal were characterized using UV-Vis spectrophotometer and Zeta potential techniques. UV-Vis spectrophotometer exhibited two peaks of absorption of CuO NPs colloidal: sharp peak at 200 nm and another peak at 630 nm. Zeta potential technique showed negative charge of CuO NPs colloidal (-28.16 mV). The morphological properties of CuO NPs such as particle size, shape and particle size distribution were characterized using Transmission Electron Microscopy (TEM) and Atomic Force Microscopy (AFM), the shapes were spherical and the particle size distribution was inhomogeneous which ranges between 20 to 180 nm. The synthesized CuO NPs presented suitable fungistatic activity against T.rubrum and its highest growth-inhibitory effectiveness was at high concentration (100 µg/ml) and high exposure time (3 hrs). Moreover, the inhibition rate of T. rubrum progressively increased with increasing CuO NPs concentration and exposure time.

Effect of Ar gas on the physical properties of Cadmium Sulfide diode prepared by PL deposition

“…[4]. These films can be used in numerous technologies, such as window layers in solar cells [5], photo sensors [6], transistors [7], diodes [8], , optical waveguides, and non-linear optical devices [9,10], due to their intriguing structural, optical, and electrical properties that are very different from bulk materials. Some of the methods that have been used to create cadmium sulfide films(CdS) such as, thermal vacumm evaporation [11], chemical deposition [12], sputtering [13], thearmal spray pyrolysis [14], and pulsed laser deposition [15][16][17].…”

“…Figure(9) indicates the relationship between lnб and 1000/T for CdS films, the activation energy can be determined by using the relation[1]:…”