Copper Supported Imidazolylpyridine Modified SPION as an Efficient Catalyst for Eco-friendly, One-pot and Green Synthesis of Novel (3- Cyanothiophen-2-yl)-N-(arylsulfonyl)acetimidamide Derivatives

Abstract

Background: In this paper, a novel catalyst is synthesized and characterized by immobilization of copper onto imidazolylpyridine modified super paramagnetic iron oxide nanoparticles (SPION). Methods: The catalyst is characterized by several methods, including TEM, SEM, ICP, DLS, and VSM. The catalytic activity of the catalyst is evaluated in the synthesis of thiosolfunamide. The synthesized catalyst showed very good activity in the mentioned reaction and showed very good performance for the synthesis of the desired products in high isolated yields. Results: For the synthesis of the products, sequential transformations enable the facile synthesis of complex target molecules from simple building blocks in a single preparative step. Conclusion: Using terminal alkynes and sulfonyl azides as starting materials, the reaction can be performed with high yield using water and ethanol as the reaction green solvent. The reusability of the catalyst was tested and the results proved the high reusability of the catalyst.