Core/Sheath-Structured Composite Nanofibers Containing Cinnamon Oil: Their Antibacterial and Antifungal Properties and Acaricidal Effect against House Dust Mites

Abstract

This study aimed to fabricate core/sheath-structured composite nanofibers containing cinnamon oil by emulsion electrospinning and to investigate their acaricidal effect on house dust mites as well as their antibacterial and antifungal properties in relation to cinnamon oil concentration in the nanofibers. An oil-in-water emulsion, which comprised cinnamon oil and poly(vinyl alcohol) solution as oil and water phases, respectively, was used to prepare core/sheath-structured nanofibers. The morphology and the inner structure of the electrospun nanofibers were observed by scanning electron microscopy and confocal laser scanning microscopy. Core/sheath-structured nanofibers containing cinnamon oil were successfully prepared by emulsion electrospinning. The composite nanofibers prepared from an emulsion containing 20 wt% of cinnamon oil exhibited a strong acaricidal effect against house dust mites (Dermatophagoides farinae). The composite nanofibers fabricated from an emulsion containing 4.29 wt% of cinnamon oil showed excellent antimicrobial effects against Staphylococcus aureus and a series of fungi that can trigger respiratory- and skin-related diseases. The release profile of cinnamon oil from the core/sheath-structured nanofibers showed a continuous release of functional ingredients over 28 days. Our findings demonstrate that the use of such fibrous structures could be a promising approach for delivering naturally derived bioactive agents in a controlled way.

Synthesis of nano-fibers containing nano-curcumin in zein corn protein and its physicochemical and biological characteristics

“…In this regard, the emulsion method has received much attention in recent decades due to containing a simple synthesizing process and high efficiency, as well as requiring low costs, and eco-friendly materials [52][53][54][55][56] . This method has been exerted to synthesize water-insoluble substances 57,58 , oils 59,60 , plant extracts 61,62 , proteins 63 , nucleic acids 64 , curcumin, and many other substances 49 for drug delivery intentions, while some of these materials have been evaluated even in nanofiber scaffolds [65][66][67] . According to the available data, there has not been any studies conducted on the usage of O/W nano-emulsion of curcumin in nanofiber substrates.…”

Encapsulation of Flavours and Fragrances into Polymeric Capsules and Cyclodextrins Inclusion Complexes: An Update

“…Core/shell nanofibers containing cinnamon oil were also successfully obtained by the emulsion electrospinning technique, using poly(vinyl alcohol) as the water phase. These nanofibers contained up to 20% w / w of cinnamon oil and showed a continuous release of the major volatile components (cinnamaldehyde, eugenol and caryophyllene) for up to 28 days [ 67 ]. Recently, another electrospinning technique has been proposed, i.d.…”

Electrospinning based on benign solvents: current definitions, implications and strategies

“…99 Cinnamon oil as the antifungal and acaricidal active component of choice was incorporated into an aqueous PVA solution with the help of Tween 80 by Lee and coworkers. 100 In a comprehensive biological study, the authors established the inhibiting effect of the 250–500 nm thick and up to 30 wt% oil-containing fibers on microbes, bacteria, and fungi. Moreover, they used the analog system with phytoncide and palmarosa oil coupled with heat treatment at 170 °C for PVA layer stabilization in order to achieve both antimicrobial and water absorption capabilities, which promises potential wound treatment applications.…”