Core-shell magnetic molecularly imprinted polymers used rhodamine B hydroxyproline derivate as template combined with in situ derivatization for the specific measurement of L-hydroxyproline

A kind of molecularly imprinted polymers modified with biocompatible medium was prepared by suspension polymerization. The obtained hybrid materials were used as the adsorbents for the solid‐phase extraction of aflatoxins B1 in real samples. A structural analog of the target, 6‐methyl‐4‐phenylchroman‐2‐one was used as the pseudo‐template, owing to their lower toxicity and cheaper price compared with aflatoxins B1; and methacrylic acid and glycidyl methacrylate were used as the co‐monomers. Scanning electron microscopy and size distribution analysis were used to characterize the obtained polymers. The extraction parameters were optimized to achieve the desired extraction performance. The polymer solid‐phase extraction coupled with high‐performance liquid chromatography was successfully applied to determine aflatoxins B1 from soy sauce without the process of protein removal. Under the optimum extraction conditions, the detection results of aflatoxins B1 in lab‐made column in soy sauce samples was carried out, with a recovery rate of 96%. The established method presented a linear range from 10 to 1000 ng/mL with the coefficient of determination of 0.9994 and the limit of detection of 0.05 ng/mL. Likewise, the inherent selectivity of lab‐made column towards aflatoxins B1, Ochratoxin A, and Zearalenone was demonstrated.

Section: Resultsmentioning

confidence: 99%

“…Four milliliters (10 μg/mL) AFB1 solution (prepared in methanol-water) was added into the tubes. The mixture was vigorously shaken at 2500 rpm for a series of time (1,2,3,6,9,12,15,20,25,30,35,40, and 60 min). The tubes were centrifuged and the supernatants were measured by HPLC.…”

Section: Dynamics Of Polymersmentioning

confidence: 99%

Combined biocompatible medium with molecularly imprinted polymers for determination of aflatoxins B1 in real sample

Song

Chen

et al. 2019

“…However, COPs tend to lack specific molecular bonding ability. To address this issue, molecularly imprinted polymers (MIPs) have been widely studied, mainly due to its ability of selective recognition for the target molecule and their structural analogues . Novel molecularly imprinted covalent organic polymers (MICOPs) that combine the outstanding properties of both COPs and MIPs are therefore expected to be the popular adsorption media for trace analysis of FWAs in food.…”

Section: Introductionmentioning

confidence: 99%

Molecularly imprinted covalent organic polymers for the selective extraction of benzoxazole fluorescent whitening agents from food samples

Ding

Wang

et al. 2018

Self Cite

Molecularly imprinted covalent organic polymers were constructed by an imine-linking reaction between 1,3,5-triformylphloroglucinol and 2,6-diaminopyridine and used for the selective solid-phase extraction of benzoxazole fluorescent whitening agents from food samples. Binding experiments showed that imprinting sites on molecularly imprinted polymers had higher selectivity for targets compared with those of the corresponding non-imprinted polymers. Parameters affecting the solid-phase extraction procedure were examined. Under optimal conditions, actual samples were treated and the eluent was analyzed with high-performance liquid chromatography with diode-array detection. The results showed that the established method has a wide linearity, satisfactory detection limits and quantification limits, and acceptable recoveries. Thus, this developed method possesses the practical potential for the selective determination of benzoxazole fluorescent whitening agents in complex food samples.

“…To resolve these difficulties, the development of reliable sample pretreatment methods for extraction of PAHs with high efficiency is of particular significance. Till now, many sample pretreatment methods have been developed and employed to purify and enrich targets before instrumental analyses, such as LLE , SPE , SPME , and so on. Among various pretreatment methods, dispersive microSPE was demonstrated to be a simple, environment‐friendly, and wide suitable method .…”

Section: Introductionmentioning

confidence: 99%

A stable mesoporous metal‐organic framework as highly efficient sorbent of dispersive micro solid‐phase extraction for the determination of polycyclic aromatic hydrocarbons by HPLC

Xia

Liu

Dou

et al. 2018

Self Cite

Owing to the large molecular sizes of polycyclic aromatic hydrocarbons, their adsorption using microporous sorbents leads to a low adsorption capacity. Here, to increase the extraction capacity and detection sensitivity of polycyclic aromatic hydrocarbons, a highly efficient dispersive micro solid-phase extraction method was developed based on a stable mesoporous metal-organic framework named Jilin University China 48. Jilin University China 48 is a super hybrid with large one-dimensional hexagonal nanotube-like channels of 24.5 × 27.9 Å, which exhibits high potential to be an efficient sorbent of dispersive micro solid-phase extraction to adsorb polycyclic aromatic hydrocarbons. By combining with high-performance liquid chromatography, a sensitive method was developed for the determination of seven polycyclic aromatic hydrocarbons. The synthesized Jilin University China 48 exhibited excellent characteristics of stability, good morphology, large surface area, and open adsorption sites. Under the optimized extraction conditions, better extraction results were obtained than that of other methods reported previously. The proposed method exhibited high sensitivity with the limit of detections in the range of 0.021-0.13 ng/mL, good linearity in the range of 0.068-50 ng/mL with related coefficients of >0.9988, satisfactory precision with relative standard deviation of <4.3%, and adequate recoveries between 85.8 to 109.55% for all the target compounds.