Core–shell structures with noble-metal nanoparticles for surface-enhanced Raman spectroscopy

A sandwich SERS immunoassay platform based on a single-layer Au–Ag nanobox array substrate for simultaneous detection of SCCA and survivin in serum of patients with cervical lesions

“…It is well known that SERS enhancement is mainly caused by the enhancement of electromagnetic fields. 47 Since SERS enhancement could be approximated as | E / E 0 | 4 , FDTD simulations were performed To predict electric field enhancement and distribution in Au–AgNBs array substrates. All geometric parameters for simulations were consistent with the actual average size of as-prepared specimens illustrated in SEM images ( Fig.…”