Corn Silk Tea and Enuresis

Kruesi, Markus J.P.

doi:10.1089/cap.2012.0125

Cited by 3 publications

(3 citation statements)

References 11 publications

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“…Corn silk, an important TCM comprising the dried yellowish stigma and silk of corn fruit, has been widely applied for disorders such as diabetes , cancer , obesity , hypertension , inflammation , fatigue , and others . Modern studies elucidated that corn silk consists of numerous constituents such as polysaccharides , flavonoids , diterpenoids , alkaloids , steroids , and more . However, until now, the overall constituents of corn silk aqueous extract, especially the bioactive constituents, still remain unclear.…”

Section: Introductionmentioning

confidence: 99%

Rapid analysis and characterization of multiple constituents of corn silk aqueous extract using ultra‐high‐performance liquid chromatography combined with quadrupole time‐of‐flight mass spectrometry

Wang

Liu

Fan

et al. 2019

J of Separation Science

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Corn silk is a well‐known traditional Chinese medicine that has been widely used for its antidiabetic, antioxidant, antihyperlipidemic, and other effects in China for thousands of years. Numerous studies have revealed that corn silk contains multiple bioactive constituents that are beneficial for human health. However, the constituents of corn silk in vivo remain ambiguous. In this study, high‐throughput ultra‐high‐performance liquid chromatography combined with quadrupole time‐of‐flight mass spectrometry technology using multivariate statistical analysis was established to systematically investigate the constituents migrating into blood from corn silk aqueous extract. As a result, 76 compounds were identified, including caffeic acid and ten of its derivatives, (E)‐p‐coumaric acid and two of its derivatives, ferulic acid and four of its derivatives, and five flavones. Among the identified constituents, 21 constituents, including nine prototype components and 12 metabolites derived from eight components, were characterized in sequence. Based on the significance of the results, the applied approach was powerful for the accurate determination and rapid screening of bioactive components from corn silk aqueous extract. The obtained results are valuable for the in‐depth understanding and further pharmacological study of corn silk aqueous extract.

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Section: Introductionmentioning

confidence: 99%

Rapid analysis and characterization of multiple constituents of corn silk aqueous extract using ultra‐high‐performance liquid chromatography combined with quadrupole time‐of‐flight mass spectrometry

Wang

Liu

Fan

et al. 2019

J of Separation Science

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show abstract

“…In multiple ancient books and local standards of Chinese medicinal materials, corn silk was recorded with multiple effects like diuretic and detumescent, liver and gallbladder protection. Modern pharmacological studies showed that corn silk could be anti-diabetic [ At present, there are a variety of health products in the market, such as corn silk tea [13,14], health-care food [15], and supplements [16]. This showed that corn silk not only owned high medicinal value, but also expressed excellent health care function.…”

Section: Introductionmentioning

confidence: 99%

“…Besides, in clinical practice, corn silk was usually used as prescriptions combined with other TCMs, especially Xiaoke Pill [10, 11], and folk formula [12]. At present, there are a variety of health products in the market, such as corn silk tea [13, 14], health‐care food [15], and supplements [16]. This showed that corn silk not only owned high medicinal value, but also expressed excellent health care function.…”

Section: Introductionmentioning

confidence: 99%

Phytochemical study: Fragmentation patterns of flavonoid‐C‐glycosides in the enriched flavonoids from corn silk using high‐efficiency ultra‐high‐performance liquid chromatography combined with quadrupole time‐of‐flight mass spectrometry

Wang,

Gu,

Mao

et al. 2023

Separation Science Plus

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Flavonoid‐C‐glycosides with various pharmacological actions were abundant in corn silk, and fragmentation in mass spectra of flavonoid‐C‐glycosides compounds was particularly important. This paper aimed to supervise the fragmentation patterns of flavonoid‐C‐glycosides in the enriched flavonoids from corn silk by high‐efficiency ultra‐high‐performance liquid chromatography combined with a quadrupole time‐of‐flight mass spectrometry approach. Therefore, the flavonoids were extracted by heating reflux and then purified based on D101 macroporous resin. Thirty‐five flavonoids were triumphantly identified in the purified product. Among them, 14 were flavonoid‐C‐glycosides, seven of them owned luteolin mother nuclei (luteolin‐C‐glycosides) and seven of them owned apigenin mother nuclei (apigenin‐C‐glycosides). Importantly, the diagnostic product ions of luteolin‐C‐glycosides including m/z (431, 413, 395, 369, 367, 313, and 299) and m/z (429, 411, 393, 367, 365, 311, and 297), and the characteristic product ions of apigenin‐C‐glycosides covered m/z (353, 339, and 299) and m/z (339, 327, and 309). In addition, diagnostic H2O neutral loss and glycosyl craking were familiar, and the difference values among product ions mainly contained 40, 60, 70, 80, 90, 100, and 120 Da. Thus, the fragmentations of luteolin‐C‐glycosides and apigenin‐C‐glycosides identified in corn silk were with proper regularity. The obtained fragmentation patterns provided rapid recognition and meaningful guidance for the purification study of flavonoid‐C‐glycosides.

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Authentication, chemical profiles analysis, and quality evaluation of corn silk via DNA barcoding and UPLC-LTQ/Orbitrap MS chemical profiling

Huang

Zhu

et al. 2023

Food Research International

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Corn Silk Tea and Enuresis

Cited by 3 publications

References 11 publications

Rapid analysis and characterization of multiple constituents of corn silk aqueous extract using ultra‐high‐performance liquid chromatography combined with quadrupole time‐of‐flight mass spectrometry

Rapid analysis and characterization of multiple constituents of corn silk aqueous extract using ultra‐high‐performance liquid chromatography combined with quadrupole time‐of‐flight mass spectrometry

Phytochemical study: Fragmentation patterns of flavonoid‐C‐glycosides in the enriched flavonoids from corn silk using high‐efficiency ultra‐high‐performance liquid chromatography combined with quadrupole time‐of‐flight mass spectrometry

Authentication, chemical profiles analysis, and quality evaluation of corn silk via DNA barcoding and UPLC-LTQ/Orbitrap MS chemical profiling

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