Corneal Densitometry as an Indicator of Corneal Health

Otri, Ahmad Muneer; Fares, Usama; Al-Aqaba, Mouhamed; Dua, Harminder S.

doi:10.1016/j.ophtha.2011.08.024

Cited by 179 publications

(149 citation statements)

References 18 publications

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“…Previously, some literatures [2,15] reported significantly increase of corneal density with age and some reported contradictory findings [4,16,17]. However, this study observed a significant increase in corneal density of about 2-3 GSU with each increment of a decade of age.…”

Section: Discussioncontrasting

confidence: 59%

Normal Values of Corneal Optical Densitometry Using Pentacam Scheimpflug Camera

Asrar¹,

Ikram²,

Khan³

et al. 2016

AOVS

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Purpose: The purpose of the study was to illustrate the range of normal values of corneal densitometry using Pentacam Scheimpflug camera. Methodology:Prospective study was conducted at tertiary care Amanat eye hospital. 490 eyes of 490 participants of different age groups were added. All scans were performed in diagnostics room with uniform ambient light, performed by trained ophthalmic technologist. All participants were Pakistani of different ethnic groups. Only one eye of each participant was included to control biasness. T test, One-way ANOVA, pearson correlation coefficient and linear regression model tests were applied for analysis.Results: 490 eyes; 247 right eyes and 243 left eyes were analyzed. Mean age was 41.7±15.27 years (range 20-81 years) with 48.4% male and 51.6% females. based on corneal depth; highest backward scattering of light was observed in anterior (120 µm) layer (20.6±8.52 GSU) than central and posterior layers 13.6±5.17 GSU and 11.7±3.99 GSU respectively. The difference was statistically significant among layers with p< 0.001. Based on corneal surface, minimum backscattering was noted in central 0-6mm zone which increases from central to limbal zone; 0-2mm zone was 13.2±3.81 GSU, 2-6mm zone was 12.6±3.68 GSU, 6-10mm zone was 16.0±8.90 GSU and 10-12mm zone was 22.1±8.26 GSU. The difference was statistically significant with p<0.001. Significant correlation of corneal densitometry and age was observed r= 0.677, p<0.001. Conclusion:Objective assessment of corneal densitometry can be made with Pentacam Scheimpflug. Normative values of corneal density may be used in routine clinical practice and provided a reference for future research.

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Section: Discussioncontrasting

confidence: 59%

Normal Values of Corneal Optical Densitometry Using Pentacam Scheimpflug Camera

Asrar¹,

Ikram²,

Khan³

et al. 2016

AOVS

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show abstract

“…Mean corneal densitometry in healthy adults has been recently reported as 12.3±2.4 and 19.7±3.9 GSU in two different studies. 6,7 The right and left corneal densitometry values were also found to be highly correlated in a previous study. 7 However, the corneal densitometry of our patient was 18.6 GSU in the affected eye and 15.7 GSU in the fellow eye.…”

Section: Discussionsupporting

confidence: 63%

“…Densitometry of the corneal tissue provides information about the clarity of the cornea. 6 The densitometry output is expressed in GSU and ranged from 0 (no clouding, maximum transparency) to 100 (completely opaque cornea, no transparency). Mean corneal densitometry in healthy adults has been recently reported as 12.3±2.4 and 19.7±3.9 GSU in two different studies.…”

Section: Discussionmentioning

confidence: 99%

Corneal Biomechanical Properties and Densitometry in a Case with Iridocorneal Endothelial Syndrome

Şekeroğlu¹,

Anayol²,

Cankaya³

et al. 2016

Turkiye Klinikleri J Ophthalmol

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“…Corneal densitometry has been studied in some ocular conditions such as bacterial keratitis, 21 Fuchs' endothelial dystrophy, 22 and keratoconus, 23 and following different procedures such as corneal transplant (DALK) 24 or crosslinking for keratoconus. 25 This is the first study of corneal densitometry in patients undergoing refractive surgery with either PRK, LASIK-FS, or ReLEx SMILE, using the latest Oculus Pentacam system software.…”

Section: Discussionmentioning

confidence: 99%

“…Densitometry measurement with the Pentacam system maybe a useful and objective tool for evaluating postoperative corneal transparency. 21 Thus, densitometry measurements will give refractive surgeons an objective measure of the corneal response and haze, allowing these to be monitored over time.…”

Section: Discussionmentioning

confidence: 99%