Corneal intraepithelial neoplasia as a cause of visual acuity decrease: a low-cost approach

Abstract

Introduction: Intraepithelial corneal neoplasia is a dysplastic disease within the spectrum of ocular surface squamous neoplasia. It is a rare disease that is often subdiagnosed, especially when it presents in its diffuse form. When suspected, the diagnosis and treatment can be simple, even when we are dealing with a disease that can be disastrous. Case report: We present the case of a 63 year-old male patient that presents complaining of poor vision on the right eye with 2 weeks of evolution. Visual acuity maintained at 20/40 while corrected and at examination showed a superior corneal geographical lesion with frosted appearance. After other diseases were discarded, an epithelial scraping was performed and a low grade intraepithelial corneal neoplasia reported. Treatment with two series of 2 weeks of mitomycin C at 0.02% with three applications per day was decided accompanied with fluorometholone 0.1% at same dosage. Conclusions: The authors recommend the use of mytomicin C in countries in developing countries.