Coronary artery calcification and emphysema

Independent association of subclinical coronary artery disease and emphysema in HIV‐infected patients

“…Our results demonstrate an independent relationship between emphysema and CAD in HIV infection after adjustment for traditional risk factors for CVD, as previously shown in the general population [22]. Unlike the general population, however, the prevalence of emphysema in this cohort was strikingly high (35%) considering the relatively young age of the patients [mean (± SD) age 48.4 ± 7.6 years].…”

“…previously shown in the general population [22]. Unlike the general population, however, the prevalence of emphysema in this cohort was strikingly high (35%) considering the relatively young age of the patients [mean (± SD) age 48.4 ± 7.6 years].…”

Relationship and Prognostic Value of Modified Coronary Artery Calcium Score, FEV1, and Emphysema in Lung Cancer Screening Population: The MILD Trial

“…The rationale of such analysis comes from previous observations suggesting a link between emphysema and CAC (11)(12)(13)(14). In a study involving electron-beam CT ( 12 ), 19% of subjects (310 of 1642) without emphysema had CAC scores of 100 or higher, compared with 31% of subjects (24 of 78) with emphysema that was visually scored.…”

“…In addition, reduced forced expiratory volume in 1 second (FEV 1 ) at pulmonary function testing has been shown to be another marker for CAD and mortality from cardiovascular disease (8)(9)(10). It has also been suggested that individuals with pulmonary emphysema have a higher prevalence of CAD (11)(12)(13)(14).…”

Association between Impaired Lung Function and Cardiovascular Disease. Cause, Effect, or Force of Circumstance?

“…Previous observational studies examining atheroma burden in relation to lung function and emphysema have yielded variable results (7)(8)(9)(10)(11)(12). In the Multi-Ethnic Study of Atherosclerosis study, coronary artery calcification was not associated with FEV 1 after adjusting for age, sex, and additional risk factors (12).…”