Coronary Artery Disease (Cad); Intermediate Cad With FFR (Fraction Flow Reserve) Evaluation

Abstract

ABSTRACT… Background: Coronary artery lesion severity is physiological assessed by fractional myocardial flow reserve (FFR) FFR assessment was done using FFR wire during maximal blood flow (hyperemia) which was induced by injecting bolus dose of intracoronary adenosine. The cost of procedure was managed by hospital. Results: In this study, 28.33% (n=17) were between 20-50 years of age, mean+SD was calculated as 55.17+8.04 years, 51.67% (n=31) were male and 48.33% (n=29) were females. Correlation between mean lesion length of diffuse intermediate stenosis (40%-70% stenosis) of proximal and mid segment of major coronary arteries and mean fractional flow reserve (FFR) was recorded it shows that mean lesion length was 24.53+4.78 mm while FFR was recorded as 0.72+0.12, the value of R is -0.1928, technically a negative correlation, the relationship between variables is only weak (the nearer the value is to zero, the weaker the relationship). The value of R 2 , the coefficient of determination, is 0.0372. Conclusion: The correlation between mean lesion length of diffuse intermediate stenosis (40%-70% stenosis) of proximal and mid segment of major coronary arteries and mean fractional flow reserve (FFR) was weak and did not suggest any hemodynamic significance of diffuse intermediate coronary artery lesions.