Coronary Artery Spasm Demonstrated by Coronary Angiography in a Patient with Acute Myocarditis Resembling Acute Myocardial Infarction; A Case Report.

Iwasaki, Kohichiro; Kusachi, Shozo; Tominaga, Yoshihiro; Kita, Toru; Taniguchi, G

doi:10.2169/internalmedicine1962.30.573

Cited by 10 publications

(8 citation statements)

References 6 publications

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“…In our series 21 of the 100 patients underwent coronary angiography or cardiac CT, all had normal or non-significant coronary artery disease. Coronary spasm in myocarditis has been previously proposed [9-11], but cases of true coronary spasm proven on coronary angiography in patients with acute myocarditis/pericarditis are rare [12,13]. In a recent study [14] biopsy proven PVB19 myocarditis was strongly associated with coronary spasm induced by acetylcholine testing during coronary angiography.…”

Section: Discussionmentioning

confidence: 99%

Left ventricular function in acute inflammatory peri-myocardial diseases – new insights and long-term follow-up

Leitman

Tyomkin

Peleg

et al. 2012

Cardiovasc Ultrasound

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BackgroundUntil recently acute inflammatory peri-myocardial syndromes have been associated with global rather regional left ventricular (LV) dysfunction. Recent advances in cardiac imaging with echocardiographic techniques and magnetic resonance imaging (MRI) permit comprehensive evaluation of global and regional LV function. Our study was aimed to assess regional LV function in 100 patients with acute perimyocarditis, and correlate these findings with the clinical presentation.MethodsWe report on 100 patients with acute perimyocarditis admitted during 2008–2011, in whom LV function was assessed by semi-quantitative wall motion score analysis on conventional echo. Long-term mortality and recurrent hospitalization were also assessed.ResultsWall motion score in 100 patients with acute perimyocarditis demonstrated a significant predominance of regional wall motion abnormalities in the infero-postero-lateral LV wall. These data correspond well with speckle tracking results of a subgroup of these patients published earlier. Recent MRI data show frequent late enhancement of contrast in the infero-lateral region of the LV in patients with perimyocarditis. These observations were useful in re-classification of our patients into one of the following groups: pure or predominant pericarditis, and pure or predominant myocarditis. Over a mean period of 37 months, there was no mortality. Though recurrent hospitalizations were rather frequent, no significant differences were observed among groups.ConclusionsRegional wall motion abnormalities in the infero-postero-lateral segments of the LV are frequent in patients with acute perimyocarditis. Detailed echocardiographic examination early in the course of the disease should become a major factor in the clinical differentiation among the various clinical presentations of acute inflammatory peri-myocardial syndromes. The long-term outcome of these patients appears to be benign, though recurrent hospitalizations are not infrequent.

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Section: Discussionmentioning

confidence: 99%

Left ventricular function in acute inflammatory peri-myocardial diseases – new insights and long-term follow-up

Leitman

Tyomkin

Peleg

et al. 2012

Cardiovasc Ultrasound

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“…Myocarditis has been shown to cause variant angina and mimic AMI [4,5] and is a plausible cause in this case as our patient experienced a viral prodrome prior to his onset of pain.…”

Section: Variant Angina Was First Described By Prinzmetal In 1959mentioning

confidence: 74%

Variant angina in a 6-year-old boy

Lim

Hia

Chia

et al. 2007

International Journal of Cardiology

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“…There are several mechanisms suggested that vasoactive substances (e.g. thromboxane A2), myocarditis-induced endothelial dysfunction, smooth muscle hyperactivity may induce coronary artery spasm in acute myocarditis patients [ 12 – 14 ].…”

Section: Discussionmentioning

confidence: 99%

Coronary artery spasm due to acute myocarditis in an adolescent: a case report

Kim

Lee

et al. 2022

BMC Pediatr

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Background Myocarditis refers to the inflammation of the myocardium caused by infection or autoimmune disease that may or may not present with clinical manifestations, such as gastrointestinal symptoms, dyspnea, chest pain, or sudden death. Although myocarditis and coronary artery vasospasm may mimic ST-segment elevation myocardial infarction (STEMI) with normal coronary arteries on angiography, acute myocarditis rarely causes coronary artery spasm. Here, we report a case of coronary artery spasm with reversible electrocardiographic changes mimicking STEMI in an adolescent with acute myocarditis. Case presentation A 15-year-old boy present with sudden-onset repeated chest pain following a 3-day history of flu-like illness. Cardiac biomarkers were significantly elevated. Electrocardiography showed ST-segment elevation in the absence of detectable vasospasm on coronary angiography. These findings were consistent with the diagnosis of coronary artery spasm secondary to acute myocarditis. Treatment with immunoglobulin for 2 days improved his condition. The patient was discharged on the 12th day with complete resolution of symptoms and normalization of electrocardiogram findings. Conclusions We reported a case of coronary artery spasm due to acute myocarditis. This study highlights the importance of considering coronary artery spasm due to acute myocarditis as a differential diagnosis in patients presenting with signs of STEMI as these diseases have different medical management strategies.

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Coronary Artery Spasm Demonstrated by Coronary Angiography in a Patient with Acute Myocarditis Resembling Acute Myocardial Infarction; A Case Report.

Cited by 10 publications

References 6 publications

Left ventricular function in acute inflammatory peri-myocardial diseases – new insights and long-term follow-up

Left ventricular function in acute inflammatory peri-myocardial diseases – new insights and long-term follow-up

Variant angina in a 6-year-old boy

Coronary artery spasm due to acute myocarditis in an adolescent: a case report

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