“…In this issue of JACC: Advances , Lin et al 4 report a post-hoc analysis of sex differences in DEFINE TYPE 2 MI, a single-center prospective study of coronary anatomy among 25 males and 25 females with adjudicated type 2 MI. 5 All participants underwent CCTA during the index hospitalization for MI. Female participants with type 2 MI enrolled in the current study were significantly older than the corresponding males.…”