Coronary optical coherence tomography: A practical overview of current clinical applications

Abstract

Coronary optical coherence tomography has emerged as the most powerful in-vivo imaging modality to evaluate vessel structure in detail. It is a useful research tool that provides insights into the pathogenesis of coronary artery disease. This technology has an important clinical role that is still being developed. We review the evidence on the wide spectrum of potential clinical applications for coronary optical coherence tomography, which encompass the successive stages in coronary artery disease management: accurate lesion characterization and quantification of stenosis, guidance for the decision to perform percutaneous coronary intervention and subsequent planning, and evaluation of immediate and long-term results following intervention. © 2016 Sociedade Portuguesa de Cardiologia. Published by Elsevier España, S.L.U. All rights reserved. PALAVRAS-CHAVEAplicação clínica; Doença coronária; Intervenção coronária percutânea; Tomografia de coerência ótica Tomografia de coerência ótica coronária: uma revisão prática das aplicações clínicas atuaisResumo A tomografia de coerência ótica coronária surgiu como a modalidade de imagem in-vivo que permite a avaliação estrutural vascular mais detalhada. Trata-se de uma ferramenta valiosa em investigação, tendo contribuído para melhor entendimento da patogénese da doença coronária. Apresenta igualmente um papel importante na prática clínica, e o leque de sua aplicabilidade tem aumentado. Enquadrando na evidência disponível, discutimos neste artigo as principais aplicações da tomografia de coerência ótica coronária na prática clínica, que englobam as diferentes etapas na abordagem da doença coronária, incluindo a caracterização da lesão e quantificação da estenose, o papel na decisão de realizar angioplastia, o contributo na planificação da mesma e a avaliação dos resultados a curto e a longo prazo após a intervenção.

Intraoperative optical coherence tomography of the human thyroid: Feasibility for surgical assessment

“…Optical coherence tomography (OCT) is the optical analogue to ultrasound imaging, but uses broadband near-infrared light to produce much higher resolution images with the tradeoff of reduced imaging depth penetration 9 (1). OCT has been widely used for clinical ophthalmic imaging 10 (2) and has demonstrated clinical translation in other areas as well including gastroenterology 11–12 , dermatology 13–14 , cardiology 15–16 , and primary care 17 . OCT has also been used for cancer imaging and demonstrated the capability of imaging breast cancer intraoperatively 18–20 and in vivo within the surgical cavity 21 for real-time surgical guidance.…”

A case report of cocaine abuse, acute coronary syndrome, and eroded plaque: stent or not stent?

“…The use of a high-resolution intracoronary imaging technique has allowed in vivo identification of the morphological characteristics of the atherosclerotic plaque in the ACS. 5 …”

Optical Coherence Tomography Contribution Assessment in the Revascularization of Long Femoropopliteal Occlusive Lesions (TASC C and D): A Randomized Trial

“…-"control group", where the procedure is achieved with usual repeated 2D-angiogram acquisitions -"OCT group", where the procedure is achieved with combination of repeated 2D angiogram and OCT acquisitions (according to the protocol [16]). The randomisation will be centralised, stratified towards the coordinator centre (CHU LILLE) and completed using a randomisation table provided by the study sponsor.…”

“…[12][13][14][15]. OCT has been initially developed to explore coronary lesions and is now routinely used in coronary disease [16]. The principle is pretty similar to IVUS, although OCT uses light waves close to Infra-red (1250-1350 nm) rather than ultrasound.…”