Coronary Sinus Reducer Improves Angina, Quality of Life, and Coronary Flow Reserve in Microvascular Dysfunction

Tryon, David; Corban, Michel T.; Alkhouli, Mohamad; Prasad, Abhiram; Raphael, Claire E.; Rihal, Charanjit S.; Reeder, Guy S.; Lewis, Brad; Albers, Diana; Gulati, Rajiv; Lerman, Amir

doi:10.1016/j.jcin.2024.09.018

JACC: Cardiovascular Interventions

2024

DOI: 10.1016/j.jcin.2024.09.018

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Coronary Sinus Reducer Improves Angina, Quality of Life, and Coronary Flow Reserve in Microvascular Dysfunction

David Tryon,

Michel T. Corban,

Mohamad Alkhouli

et al.

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Cited by 3 publications

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The Reducer Is a Novel, Safe, and Effective Therapy to Optimize the Management of Patients With Stable Angina

Banai,

Lerman,

Verheye

2024

Journal of the American College of Cardiology

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The Reducer Is a Novel, Safe, and Effective Therapy to Optimize the Management of Patients With Stable Angina

Banai,

Lerman,

Verheye

2024

Journal of the American College of Cardiology

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The Coronary Sinus Reducer as a Game-Changer for the Treatment of Coronary Microvascular Dysfunction

van de Hoef

2024

JACC: Cardiovascular Interventions

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Coronary Sinus Reducer Therapy for Refractory Angina and its Role in Modern Interventional Practice: A Contemporary Review

Cheng,

Hill,

de Silva

2024

Interv Cardiol

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Coronary sinus reducer (CSR) implantation is an emerging treatment option for patients with refractory angina. This condition represents a major global cardiovascular healthcare challenge, with patients experiencing chronic anginal symptoms that significantly impair their quality of life and for whom few effective treatments exist. The clinical burden of refractory angina is only set to grow because of improved survival from coronary artery disease, increased life expectancy and the presence of residual angina after percutaneous or surgical coronary revascularisation. Therefore, new, effective, evidence-based therapies are urgently needed. In this review, we highlight the unmet clinical needs of patients with refractory angina, discuss the development of the CSR device and review the preclinical and clinical evidence base underlying CSR implantation. In addition, we discuss the current role of CSR implantation in contemporary interventional practice, highlighting knowledge gaps and discussing areas of on-going research.

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Coronary Sinus Reducer Improves Angina, Quality of Life, and Coronary Flow Reserve in Microvascular Dysfunction

Cited by 3 publications

References 29 publications

The Reducer Is a Novel, Safe, and Effective Therapy to Optimize the Management of Patients With Stable Angina

The Reducer Is a Novel, Safe, and Effective Therapy to Optimize the Management of Patients With Stable Angina

The Coronary Sinus Reducer as a Game-Changer for the Treatment of Coronary Microvascular Dysfunction

Coronary Sinus Reducer Therapy for Refractory Angina and its Role in Modern Interventional Practice: A Contemporary Review

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