Corpus luteum response to exogenous HCG during the mid‐luteal phase of the menstrual cycle

Abstract

The exogenous HCG regimes used in this study successfully mimicked the hormonal environment found in biochemical, single and multiple pregnancies and elicited appropriate corpus luteum responses.

The expression of inducible nitric oxide synthase in the human fallopian tube during the menstrual cycle and in ectopic pregnancy

“…Women were asked to have treatment with hCG in the days leading to hysterectomy. This regimen produces a state of pseudopregnancy, is harmless, and has been previously used within U.K. research studies (16,17). Six fallopian tubes were obtained from women who were undergoing routine total abdominal hysterectomy (TAH) for benign disease not affecting the fallopian tubes.…”

The Expression of Activin-βA- and -βB-Subunits, Follistatin, and Activin Type II Receptors in Fallopian Tubes Bearing an Ectopic Pregnancy

“…This regimen produces a state of pseudopregnancy, is harmless, and has been previously used within U.K. research studies (23,24). Six Fallopian tubes were obtained from women who were undergoing routine total abdominal hysterectomy for benign disease not affecting the Fallopian tubes, and they were pretreated with sc hCG (5000 IU) every 3 d beginning in the midluteal phase for at least 12 d before total abdominal hysterectomy.…”

Local and systemic factors and implantation: what is the evidence?

“…A defined period of endometrial receptivity during the mid-secretory phase also corresponds well to prime responsiveness of the corpus luteum to hCG (13, 14). In fact, evidence from the 1999 Wilcox study shows that late implanting embryos are at higher risk for miscarriage than those that implant during the window of implantation (WOI), between post ovulatory days 6 to 10 (15).…”