Correct assignment of lipophilic dye mixtures? A case study for high-performance thin-layer chromatography–mass spectrometry and performance data for the TLC–MS Interface

Molecular Ionization-Desorption Analysis Source (MIDAS) for Mass Spectrometry: Thin-Layer Chromatography

“…Interfacing TLC plate analysis with mass spectrometry has been achieved through direct coupling using sampling probes with solvent elution [2], through direct electrospray ionization from physically modified plates [3], as well as through other commercially available ambient mass spectrometry techniques such as desorption electrospray ionization (DESI) [4][5][6] and direct analysis in real time (DART) [7][8][9]. A more complete picture of this landscape can be found in these reviews [10][11][12][13].…”

Microfabrication, separations, and detection by mass spectrometry on ultrathin-layer chromatography plates prepared via the low-pressure chemical vapor deposition of silicon nitride onto carbon nanotube templates

“…Nevertheless, clear mass spectra were obtained for all dyes on the UTLC plate, except OV2R (6). correctly assigned [36]. As the 500 • C DART gas stream did not damage the UTLC layer, the reuse of these plates was also possible after DART-MS scanning.…”

Goldenrod Root Compounds Active against Crop Pathogenic Fungi

“…avenaceum . The latter method is suitable for non-targeted and effect-directed analysis (EDA) of antimicrobial compounds with considerable time and cost savings, if compared to status quo analyses for detection and isolation of individual antimicrobial compounds in complex plant extracts. ,, In the past decade, HPTLC analyses have benefited from their hyphenation to high-resolution mass spectrometry (HRMS n ), particularly through the use of elution head-based TLC–MS interfaces. ,, This supports the characterization and identification of the separated compounds of interest, e.g., the compounds responsible for the desired effect. , …”

“…12,16,17 In the past decade, HPTLC analyses have benefited from their hyphenation to highresolution mass spectrometry (HRMS n ), particularly through the use of elution head-based TLC−MS interfaces. 13,18,19 This supports the characterization and identification of the separated compounds of interest, e.g., the compounds responsible for the desired effect. 17,20 Most of the about 120 goldenrod (Solidago) species are native in North America, and three of them, i.e., Solidago canadensis L., Solidago gigantea Ait., and Solidago graminifolia (L.) Salisb., were introduced as ornamental flowers in Europe in the 19th century and have been naturalized.…”