Corrected Intraocular Pressure Variability with Central Corneal Thickness Measurement

Ahmed, Mohamed; Abdelhalim, Ahmed Shawkat

doi:10.2147/opth.s288391

Cited by 7 publications

(3 citation statements)

References 25 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…CCT has been shown to correlate positively with IOP in many studies (Table 2). [4][5][6][7][8][9] This research found a good relationship between CCT and IOP. According to statistical analysis, the observed IOP rises by 0.042 mmHg (R 2 = 0.126, p = 0.000) on the right eye and 0.038 mmHg (R 2 = 0.145, p = 0.000) on the left eye for every 100 µm increase in CCT.…”

Section: Discussionmentioning

confidence: 68%

Correlation between Central Corneal Thickness and Intraocular Pressure: A Cross Sectional Study

Alberta¹,

Ernawati²,

Rofiq³

2023

pak J Ophthalmol

View full text Add to dashboard Cite

Purpose: To find out correlation between Central Corneal Thickness (CCT) and Intra Ocular Pressure (IOP). Study Design: Observational Correlational study. Place and Duration of Study: This study was conducted in Ophthalmology Clinic Primasatya Husada Citra Hospital Surabaya from September 2021 to October 2021. Methods: One hundred and fifteen subjects were selected through consecutive sampling. Patients of 20-60 years age and visiting ophthalmology clinic were included. Patients with history of glaucoma, hypertension, body mass index (BMI) above 30 kg/m2, under steroid treatment (topical, systemic, peri ocular, inhalation), undergone eye surgery including corneal and refractive surgery, smoker (> 100 cigarettes in his/her life and is still smoking), Alcoholic (> 1 time/month), chronic kidney disease (CKD) and myopia (> 6 diopters) were excluded. Association between CCT and IOP was calculated using Pearson's correlation coefficient. Results: A total 115 patients were included, 69 (60%) females and 46 (40.0%) males. Mean age was 35.78 ± 11.64 years old. Mean CCT was 550.26 ± 31.66 µm and 551.43 ± 34.92 µm for right and left eye respectively. IOP was 16.06 ± 3.71 mmHg and 15.76 ± 3.52 mmHg in right and left eyes respectively. There was a moderate positive relationship of CCT and IOP. There was a good relationship between right and left “IOP (R = 0.830, p = 0.000) and CCT (R = 0.856, p = 0.000).” Conclusion: CCT had a moderate positive correlation with IOP (right eyes: R = 0.355, p = 0.000; left eyes: R = 0.381, P = 0.000). There is a positive relationship between CCT and IOP in both eyes (p = 0.000).

show abstract

Section: Discussionmentioning

confidence: 68%

Correlation between Central Corneal Thickness and Intraocular Pressure: A Cross Sectional Study

Alberta¹,

Ernawati²,

Rofiq³

2023

pak J Ophthalmol

View full text Add to dashboard Cite

show abstract

“…The current standard is to record an IOP measurement from a patient and use their central corneal thickness (CCT) to correct the IOP to an adjusted value. Numerous studies confirm that corneal thickness impacts IOP measurements because of the variable resistance to a tonometer probe [5][6][7]. A tonometer with CCT built into the prediction process would have no need for an adjusted IOP post measurement by the physician, but would have the adjustment built in.…”

Section: Introductionmentioning

confidence: 99%

Predicting intraocular pressure utilizing highly nonlinear solitary waves as inputs to a CNN

Hodgson,

Rizzo,

Dickerson

et al. 2024

Health Monitoring of Structural and Biological Systems XVIII

View full text Add to dashboard Cite

Highly nonlinear solitary waves (HNSWs) are traditionally used in the field of nondestructive evaluation to inspect a material's property without causing damage. The research in this paper proposes a new application for HNSWs: predicting changes in intraocular pressure (IOP) to ensure optimum treatment and prevent the progression of Glaucoma in an eye. The HNSWs used for assessment were collected from a Polydimethylsiloxane (PDMS) eye model and are initiated and stored with a solitary wave transducer. To collect a full range of HNSWs that represent the biological range of IOPs in humans, the PDMS eye model is pressurized from 12mmHg to 26mmHg with 1mmHg increments and waves are collected at each pressure point. Once a HNSW is collected, it is wirelessly transmitted to a server where it is fed into a convolutional neural network to predict the IOP. This is done by extracting relevant features from the HNSW with a Fast Fourier Transform and constructing a spectrogram which can be fed into the algorithm pixel by pixel. This methodology works due to the association of frequency content in the HNSW and changes of the stiffness in the material. In the case of high IOP, the increased pressure pushes against the artificial PDMS cornea and causes it to become stiffer with a higher Young's modulus. We evaluated the ability of the algorithm to predict IOP based on the spectrogram.

show abstract

“…7,8 It is also evident from literature that IOP may be affected by change in the CCT. 9,10 This can cause errors in readings of IOP and may lead to false diagnosis of secondaryglaucoma. 11,12 Doughty and Zaman reported that a 10% change in CCT may cause 3.4mmHg change in IOP.…”

Section: Introductionmentioning

confidence: 99%

Effect of Pars Plana Vitrectomy on Central Corneal Thickness and Its Influence onIntraocular Pressure

Zia,

Kazi,

Ghazipura

et al. 2023

pak J Ophthalmol

View full text Add to dashboard Cite

Purpose: To determine the effect of Pars Plana Vitrectomy on the central corneal thickness(CCT)and its influence on intraocular pressure(IOP). Study Design: Interventional case series. Place and Duration of Study: This research was conducted at Ibrahim Eye Hospital, Karachi, Pakistan, from October 2022 to March 2023. Methods: Forty-one patients of either sexpresenting with posterior segment disease and planned for Pars Plana vitrectomy (PPV) were selected after written informed consent. Pre and post-operative comparison of CCT and IOP was done using paired t-test. Follow-up of readings was done by repeated measures ANOVA test. BCVA measurements were based on the Snellen chart and were converted to the logarithm of the minimum angle of resolution (logMAR) scale for statistical analysis. Results: CCT and IOP of the affected eyes were increased considerably in the first post-operative week (CCT=591 ± 1.5,IOP=28 ± 1.5)and decreased significantly in the 3rd month(CCT=527 ± 1.34, IOP=13 ± 2.5). The change was insignificant at 6thmonth follow-up. BCVA was improved in first week (626 ± 1.34) and remained same throughout the follow-up period. Maximum change in CCT (ΔCCT)was found in age <15 years and in aphakic eyes (119 ± 0.09). Conclusion: Pars Plana vitrectomy causes significant change in CCTwhich can influenceIOP. This change should be kept in mind to prevent false diagnosis of glaucoma in the early post-operative period of PPV. Young patients and Aphakic eyes are more prone to the corneal changes.

show abstract

Corrected Intraocular Pressure Variability with Central Corneal Thickness Measurement

Cited by 7 publications

References 25 publications

Correlation between Central Corneal Thickness and Intraocular Pressure: A Cross Sectional Study

Correlation between Central Corneal Thickness and Intraocular Pressure: A Cross Sectional Study

Predicting intraocular pressure utilizing highly nonlinear solitary waves as inputs to a CNN

Effect of Pars Plana Vitrectomy on Central Corneal Thickness and Its Influence onIntraocular Pressure

Contact Info

Product

Resources

About