Correction: Ha, Y. et al. Hemispherical Microelectrode Array for Ex Vivo Retinal Neural Recording. Micromachines 2020, 11, 538

Ha, Yoonhee; Yoo, Hyun Ji; Shin, Soowon; Jun, Sang Beom

doi:10.3390/mi11080720

Cited by 4 publications

(4 citation statements)

References 1 publication

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“…Tricyclic systems can be generated through the reaction of fused bicyclic alkenes (48 to 52) with products being formed in 34 to 90% yield. Notably, N-methylmaleimide also reacts in this transformation forming 53, enabled by its comparable triplet energy to styrene (55.9 kcal/mol) (47). The formation of this product shows the versatility of this method beyond styrenes and dienes.…”

Section: Reaction Developmentmentioning

confidence: 91%

Visible light–mediated aza Paternò–Büchi reaction of acyclic oximes and alkenes to azetidines

Wearing,

Yeh,

Terrones

et al. 2024

Science

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The aza Paternò–Büchi reaction is a [2+2]-cycloaddition reaction between imines and alkenes that produces azetidines, four-membered nitrogen-containing heterocycles. Currently, successful examples rely primarily on either intramolecular variants or cyclic imine equivalents. To unlock the full synthetic potential of aza Paternò–Büchi reactions, it is essential to extend the reaction to acyclic imine equivalents. Here, we report that matching of the frontier molecular orbital energies of alkenes with those of acyclic oximes enables visible light–mediated aza Paternò–Büchi reactions through triplet energy transfer catalysis. The utility of this reaction is further showcased in the synthesis of epi- penaresidin B. Density functional theory computations reveal that a competition between the desired [2+2]-cycloaddition and alkene dimerization determines the success of the reaction. Frontier orbital energy matching between the reactive components lowers transition-state energy (Δ G ǂ ) values and ultimately promotes reactivity.

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Section: Reaction Developmentmentioning

confidence: 91%

Visible light–mediated aza Paternò–Büchi reaction of acyclic oximes and alkenes to azetidines

Wearing,

Yeh,

Terrones

et al. 2024

Science

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“…In oocyte overexpression TRPP1 forms functional homomeric and heteromeric channels. Gain of function mutations in TRPP1 in either the S4-S5 linker (F604P) or in the lower gate (L677A, N681A) result in constitutively active channels [41,420,1301]. TRPP1 prefers monovalent cations over divalent cations in the order of K + >Na + >Ca 2+ (permeability 1:0.4:0.025), showing low selectivity for Ca 2+ .…”

Section: Commentsmentioning

confidence: 99%

“…The conductance of TRPP1 varies depending on the ion (K + : 144 pS, Na + : 89 pS, Ca 2+ : 4pS) [722]. TRPP1 homomeric channel produces a larger conductance of 82 pS than the PC-1/TRPP1 heteromeric channel (79.5 pS) with higher absolute open probability (TRPP1 homomeric channel: 0.58, PC-1/TRPP1 heteromeric channel: 0.08) in primary cilia [420]. Specific activators or channel blockers of TRPP1 remain unknown.…”

Section: Commentsmentioning

confidence: 99%

The Concise Guide to PHARMACOLOGY 2023/24: Ion channels

Alexander,

Mathie,

Peters

et al. 2023

British J Pharmacology

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The Concise Guide to PHARMACOLOGY 2023/24 is the sixth in this series of biennial publications. The Concise Guide provides concise overviews, mostly in tabular format, of the key properties of approximately 1800 drug targets, and over 6000 interactions with about 3900 ligands. There is an emphasis on selective pharmacology (where available), plus links to the open access knowledgebase source of drug targets and their ligands (https://www.guidetopharmacology.org/), which provides more detailed views of target and ligand properties. Although the Concise Guide constitutes almost 500 pages, the material presented is substantially reduced compared to information and links presented on the website. It provides a permanent, citable, point‐in‐time record that will survive database updates. The full contents of this section can be found at http://onlinelibrary.wiley.com/doi/10.1111/bph.16178. Ion channels are one of the six major pharmacological targets into which the Guide is divided, with the others being: G protein‐coupled receptors, nuclear hormone receptors, catalytic receptors, enzymes and transporters. These are presented with nomenclature guidance and summary information on the best available pharmacological tools, alongside key references and suggestions for further reading. The landscape format of the Concise Guide is designed to facilitate comparison of related targets from material contemporary to mid‐2023, and supersedes data presented in the 2021/22, 2019/20, 2017/18, 2015/16 and 2013/14 Concise Guides and previous Guides to Receptors and Channels. It is produced in close conjunction with the Nomenclature and Standards Committee of the International Union of Basic and Clinical Pharmacology (NC‐IUPHAR), therefore, providing official IUPHAR classification and nomenclature for human drug targets, where appropriate.

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“…Traditionally MEMS stencils have been largely fabricated using laser micromachining, CNC milling, DRIE, and other photolithographic approaches due to their allowances for great precision and ease of workflow integration. However, with lengthier processing times, high cost and accessibility concerns, these technologies have become much less appealing [3,4]. Technologies such as plotter cutters and electronic cutters [5] with extreme process optimization could replace older stencil masking technologies.…”

Section: Introductionmentioning

confidence: 99%

Rapid Cost-Effective Plotter Cut Stencil Masks for the Deposition of Organic and Inorganic Materials and the Creation of a New Antibiotic Diffusion Test for Minimal Lethal Concentration Detection

Childs,

Pereira,

Baksh

et al. 2022

2022 Solid-State, Actuators, and Microsystems Workshop Technical Digest

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The use of plotter cutters in stencil mask prototyping is underutilized but has several advantages over traditional MEMS techniques. In this paper we investigate the use of a conventional plotter cutter as a highly effective benchtop tool for rapid prototyping of stencil masks in the sub-100μm range and characterize patterned layers of different organic/inorganic materials. Furthermore, a diagnostic monitoring application in healthcare and a potential replacement of Standard Kirby-Bauer (KB) Diffusion Antibiotic Resistance Tests [1, 2] allowing for three times the amount of Antibiotics to be tested within the same nutrient agar petridish are demonstrated.

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Correction: Ha, Y. et al. Hemispherical Microelectrode Array for Ex Vivo Retinal Neural Recording. Micromachines 2020, 11, 538

Abstract: The authors would like to make the following changes to the published paper [...]

Cited by 4 publications

References 1 publication

Visible light–mediated aza Paternò–Büchi reaction of acyclic oximes and alkenes to azetidines

Visible light–mediated aza Paternò–Büchi reaction of acyclic oximes and alkenes to azetidines

The Concise Guide to PHARMACOLOGY 2023/24: Ion channels

Rapid Cost-Effective Plotter Cut Stencil Masks for the Deposition of Organic and Inorganic Materials and the Creation of a New Antibiotic Diffusion Test for Minimal Lethal Concentration Detection

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