Correction: Nanoparticle size and chemical modification play a crucial role in the interaction of nano gold with the brain: extent of accumulation and toxicity

Mahmoud, Nouf N.; Albasha, Abdulrahim; Hikmat, Suhair; Hamadneh, Lama; Zaza, Rand; Shraideh, Z.; Khalil, Enam A.

doi:10.1039/d0bm90023k

Cited by 1 publication

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“…Blood brain and cerebrospinal fluid barriers made the delivery of some drugs to the CNS of a great challenge. 54 • NE gel exhibited small droplets of a size under 100 nm • Enhancement in skin permeability and satisfactory permeation parameters • No irritation to the skin.…”

Section: Nes For Central Nervous System (Cns) Drug Deliverymentioning

confidence: 96%

Recent exploration of nanoemulsions for drugs and cosmeceuticals delivery

Abu‐Huwaij

Al‐Assaf

Hamed

2021

J of Cosmetic Dermatology

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Background: Nanoemulsions (NEs) have been explored as nanocarriers for the delivery of many drugs and cosmeceuticals. The extraordinary expansion of using NEs is due to their capability to conquer the main challenges of conventional delivery systems such as short residence time with low patient acceptance, poor stability, low aqueous solubility, permeability, and hence bioavailability. Methods:This review recapitulated the most recent pharmaceutical and cosmeceutical applications of NEs as effective delivery nanocarriers. The outputs of our research studies and the literature review on the latest NEs applications were assessed to highlight the NEs components, preparations, applications, and the improved quality and elegance of the used product.Results: NEs are stable submicronic translucent dispersions with narrow droplet size distribution. They exhibited excellent ability to efficiently encapsulate therapeutics of diverse nature of drugs and cosmeceuticals. NE formulations showed superiority over conventional delivery approaches with overabundances of advantages through different routes of administration. This novel technology exhibited better aesthetic appeal, higher bioavailability, and a longer duration compared to the conventional delivery systems. Conclusion:This novel technology holds promise for different therapeutics fields.However, the success of NEs use advocated the development of robust formulations, proper choice of equipment, ample process characterization, and assurance of their efficacy, stability, safety and cosmetic appeal.

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Section: Nes For Central Nervous System (Cns) Drug Deliverymentioning

confidence: 96%