Correction: Osterwalder et al. Acute Abdominal Pain: Missed Diagnoses, Extra-Abdominal Conditions, and Outcomes. J. Clin. Med. 2020, 9, 899

Osterwalder, Isabelle; Özkan, Merve; Malinovska, Alexandra; Nickel, Christian H.; Bingisser, Roland

doi:10.3390/jcm12041403

Cited by 1 publication

(1 citation statement)

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“…In addition, symptoms from some extra-abdominal injuries can mimic peritonitis[ 18 ]. Multiple rib fractures especially of the lower quarter ribs can commonly cause abdominal pain and abdominal muscle tension.…”

Section: Discussionmentioning

confidence: 99%

Conservative management of multi-trauma induced peritonitis: Experience, outcomes, and indications

Chen,

Zhu,

Liu

et al. 2023

World J Clin Cases

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Insulin, a small protein with 51 amino acids synthesized by pancreatic β-cells, is crucial to sustain glucose homeostasis at biochemical and molecular levels. Numerous metabolic dysfunctions are related to insulin-mediated altered glucose homeostasis. One of the significant pathophysiological conditions linked to the insulin associated disorder is diabetes mellitus (DM) (type 1, type 2, and gestational). Insulin resistance (IR) is one of the major underlying causes of metabolic disorders despite its association with several physiological conditions. Metabolic syndrome (MS) is another pathophysiological condition that is associated with IR, hypertension, and obesity. Further, several other pathophysiological disorders/diseases are associated with the insulin malfunctioning, which include polycystic ovary syndrome, neuronal disorders, and cancer. Insulinomas are an uncommon type of pancreatic β-cell-derived neuroendocrine tumor that makes up 2% of all pancreatic neoplasms. Literature revealed that different biochemical events, molecular signaling pathways, microRNAs, and microbiota act as connecting links between insulin disorder and associated pathophysiology such as DM, insuloma, neurological disorder, MS, and cancer. In this review, we focus on the insulin-related disorders and the underlying mechanisms associated with the pathophysiology.

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Section: Discussionmentioning

confidence: 99%