Correction to: Genicular artEry embolizatioN in patiEnts with oSteoarthrItiS of the Knee (GENESIS) Using Permanent Microspheres: Interim Analysis

Little, Mark W.; Gibson, Matthew; Briggs, James; Speirs, Archie; Yoong, Philip; Ariyanayagam, Timothy; Davies, Nathan; Tayton, Edward; Tavares, Shawn; MacGill, S.; McLaren, C.; Harrison, Richard

doi:10.1007/s00270-021-02849-7

Cited by 3 publications

(1 citation statement)

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“…In the treatment of modern diseases, drug-carrying microspheres are usually combined with compound microspheres with drugs, so as to achieve the drug sent to the lesion and slowly released there, which can effectively prolong the time of drug action and is a very effective means of treating diseases. At present, the application of microspheres in diseases mainly includes oncotherapy [ 183 ], skin wounds [ 68 ], bone repair [ 184 ] arthritis [ 185 ], and so on.…”

Section: Application Of Microspheres In Diseasesmentioning

confidence: 99%

Progress in the application of sustained-release drug microspheres in tissue engineering

Ruan¹,

Su²,

Qin³

et al. 2022

Materials Today Bio

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Section: Application Of Microspheres In Diseasesmentioning

confidence: 99%

Progress in the application of sustained-release drug microspheres in tissue engineering

Ruan¹,

Su²,

Qin³

et al. 2022

Materials Today Bio

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Musculoskeletal Embolotherapy: Past, Present, and Future

Little

2021

Cardiovasc Intervent Radiol

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Genicular Artery Embolization: A New Tool for the Management of Refractory Osteoarthritis-Related Knee Pain

Femia,

Valenti Pittino,

Fumarola

et al. 2024

JPM

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Osteoarthritis (OA) of the knee is a prevalent cause of chronic pain and disability, particularly affecting women. While traditionally attributed to chronic wear and tear, recent evidence highlights multifactorial pathogenesis involving low-grade inflammation and neoangiogenesis. Current therapeutic options include physical therapy, pharmacotherapy, and total knee arthroplasty (TKA). However, a subset of patients remain symptomatic despite conservative measures, necessitating the development of minimally invasive interventions. Genicular artery embolization (GAE) emerges as a promising option, targeting neovascularization and inflammatory processes in OA. This paper reviews the pathophysiological basis, patient selection criteria, procedural details, and outcomes of GAE. Notably, GAE demonstrates efficacy in relieving knee pain and improving function in patients refractory to conventional therapy. While further research is warranted to elucidate its long-term outcomes and compare it with existing modalities, GAE represents a novel approach in the management of symptomatic knee OA, potentially delaying or obviating the need for surgical intervention. Here, we synthesize the relevant literature, technical details of the procedure, and future perspectives. Moreover, the success of GAE prompts the exploration of transarterial embolization in other musculoskeletal conditions, underscoring the evolving role of interventional radiology in personalized pain management strategies.

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Correction to: Genicular artEry embolizatioN in patiEnts with oSteoarthrItiS of the Knee (GENESIS) Using Permanent Microspheres: Interim Analysis

Cited by 3 publications

References 0 publications

Progress in the application of sustained-release drug microspheres in tissue engineering

Progress in the application of sustained-release drug microspheres in tissue engineering

Musculoskeletal Embolotherapy: Past, Present, and Future

Genicular Artery Embolization: A New Tool for the Management of Refractory Osteoarthritis-Related Knee Pain

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