Correction to: MicroRNA-351 Promotes the Proliferation and Invasion of Glioma Cells through Downregulation of NAIF1

Wu, Xuanxuan; Hu, Chongling; Long, Chunxi; Zhai, Xuan; Liang, Ping; Yu, Zeng-peng

doi:10.1007/s12031-020-01655-z

Cited by 2 publications

(5 citation statements)

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“…Determining the markers that influence illness prognosis or result in treatment resistance is a goal of research on targeted medicines. [11] NAIF1 may considered as a tumor suppressor gene that is involved in a number of cellular functions, such as apoptosis, differentiation, genome stability, and survival. [3][4][5][6][7][8][9][10][11] The mechanism behind the progression of many cancers when NAIF1 expression drops or disappears totally is unclear, but its ability to trigger apoptosis provides one explanation.…”

Section: Discussionmentioning

confidence: 99%

“…[11] NAIF1 may considered as a tumor suppressor gene that is involved in a number of cellular functions, such as apoptosis, differentiation, genome stability, and survival. [3][4][5][6][7][8][9][10][11] The mechanism behind the progression of many cancers when NAIF1 expression drops or disappears totally is unclear, but its ability to trigger apoptosis provides one explanation. [3][4][5][6][7][8][9][10][11] According to our western blot analysis, the expression of NAIF1 reduced from healthy colon tissue to advanced colorectal cancer.…”

Section: Discussionmentioning

confidence: 99%

“…[3][4][5][6][7][8][9][10][11] The mechanism behind the progression of many cancers when NAIF1 expression drops or disappears totally is unclear, but its ability to trigger apoptosis provides one explanation. [3][4][5][6][7][8][9][10][11] According to our western blot analysis, the expression of NAIF1 reduced from healthy colon tissue to advanced colorectal cancer. This result is in line with earlier research on colorectal cancer tissue, it used a western blot to examine the expression of NAIF1 in healthy and cancerous tissue.…”

Section: Discussionmentioning

confidence: 99%

“…NAIF1 primary antibody (In-Cell-Art, Nantes, France) [9] application revealed particular NAIF1 expression products in all samples evaluated (transfected Hela, normal colon tissue, and stage I-III colorectal cancer tissue) with a molecular weight of 35 kDa, which is the same as the NAIF1 transposase. [10] As demonstrated in figure 2, NAIF1 expression was higher in healthy colon tissue than in colorectal cancer, particularly as the cancer progressed from stage I to stage III.…”

Section: Naif1 Expression By Western Blotmentioning

confidence: 99%

“…However, it is downregulated in osteosarcoma tissue and cell lines and can stop the spread and invasion of these tumors. [3][4][5][6][7][8][9][10][11] This study used western blot and immunohistochemistry staining to analyze the proteomic expression of NAIF1 in colorectal cancer patient samples. The association between the patients' clinicopathological features and absence of expression of this protein was then investigated.…”

Section: Introductionmentioning

confidence: 99%

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Naif1 Expression in Colorectal Cancer Patients: Clinical and Pathological Implications

QASIM¹,

SHAHAD²,

AHMED³

et al. 2022

MINAR Journal

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Background: In advanced human malignancies, the nuclear apoptosis-inducing factor 1 (NAIF1) is commonly silenced or not expressed. The purpose of this study was to look into potential relationships between clinical, pathological characteristics and NAIF1 expression. Methods: This cross-sectional study used western blot and immunohistochemistry staining to assess the level of NAIF1 expression in 100 colorectal cancer samples. The outcomes of the immunohistochemistry staining were then contrasted with those of the clinicopathological characteristics. Results: 68 out of 100 colorectal cancer samples were negative for NAIF1 expression. In contrast to other clinicopathological parameters, loss of NAIF1 expression was significantly linked with lymphovascular invasion (P=< 0.00001), angiovascular invasion (P= 0.004356) and advanced TNM tumor stage (P=0. 004077). Conclusion: According to the current study, a higher stage and a bad prognosis may be linked to decreased or negative NAIF1 expression. Keywords: Clinical, Colorectal Cancer, Expression, NAIF1, Pathological

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Naif1 Expression By Western Blotmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Naif1 Expression in Colorectal Cancer Patients: Clinical and Pathological Implications

QASIM¹,

SHAHAD²,

AHMED³

et al. 2022

MINAR Journal

View full text Add to dashboard Cite

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Non-coding RNAs and glioblastoma: Insight into their roles in metastasis

Mousavi

Derakhshan

Baharloii

et al. 2022

Molecular Therapy - Oncolytics

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Glioma, also known as glioblastoma multiforme (GBM), is the most prevalent and most lethal primary brain tumor in adults. Gliomas are highly invasive tumors with the highest death rate among all primary brain malignancies. Metastasis occurs as the tumor cells spread from the site of origin to another site in the brain. Metastasis is a multifactorial process, which depends on alterations in metabolism, genetic mutations, and the cancer microenvironment. During recent years, the scientific study of non-coding RNAs (ncRNAs) has led to new insight into the molecular mechanisms involved in glioma. Many studies have reported that ncRNAs play major roles in many biological procedures connected with the development and progression of glioma. Long ncRNAs (lncRNAs), microRNAs (miRNAs), and circular RNAs (circRNAs) are all types of ncRNAs, which are commonly dysregulated in GBM. Dysregulation of ncRNAs can facilitate the invasion and metastasis of glioma. The present review highlights some ncRNAs that have been associated with metastasis in GBM. miRNAs, circRNAs, and lncRNAs are discussed in detail with respect to their relevant signaling pathways involved in metastasis.

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Correction to: MicroRNA-351 Promotes the Proliferation and Invasion of Glioma Cells through Downregulation of NAIF1

Cited by 2 publications

References 0 publications

Naif1 Expression in Colorectal Cancer Patients: Clinical and Pathological Implications

Naif1 Expression in Colorectal Cancer Patients: Clinical and Pathological Implications

Non-coding RNAs and glioblastoma: Insight into their roles in metastasis

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