Correction to: Mitochondrial activity regulates the differentiation of skin-derived mesenchymal stem cells into brown adipocytes to contribute to hypertension

Xi, Wenda; Chen, Wendong; Sun, Weihong; Li, Xiangxiao; Suo, Zhimin; Jiang, Gonghao; Gao, Pingjin; Li, Qun

doi:10.1186/s13287-021-02408-4

Stem Cell Res Ther

2021

DOI: 10.1186/s13287-021-02408-4

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Correction to: Mitochondrial activity regulates the differentiation of skin-derived mesenchymal stem cells into brown adipocytes to contribute to hypertension

Wenda Xi

Wendong Chen

Weihong Sun

et al.

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The protective role of brown adipose tissue in cardiac cell damage after myocardial infarction and heart failure

Xu,

Li,

Cao

et al. 2024

Lipids Health Dis

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Acute myocardial infarction (AMI) and related cardiovascular disease complications are the leading causes of mortality worldwide. Brown adipose tissue (BAT) is thermogenic and characterized by the uncoupling protein expression. Recent studies have found that in cardiovascular diseases, activated BAT can effectively improve the prognosis of AMI and concurrent heart failure through intercellular communication. However, a clear and systematic understanding of the myocardial protective mechanism of BAT after AMI is lacking, especially in the endocrine function of BAT. This review describes the effects of BAT on various cells in the heart after AMI. BAT plays a protective role on cardiac cells and fibroblasts during ischemia/reperfusion (I/R), myocardial remodeling, and myocardial fibrosis. This review also discusses the changes caused by BAT activation in different stages of heart failure. Finally, this review summarizes the treatment methods that target BAT to improve AMI. Further in-depth researches are still needed to clarify the underlying mechanism of the connection between BAT and different cells in cardiac tissue in order to identify potential therapeutic targets.

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The protective role of brown adipose tissue in cardiac cell damage after myocardial infarction and heart failure

Xu,

Li,

Cao

et al. 2024

Lipids Health Dis

View full text Add to dashboard Cite

show abstract

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Correction to: Mitochondrial activity regulates the differentiation of skin-derived mesenchymal stem cells into brown adipocytes to contribute to hypertension

Cited by 1 publication

References 1 publication

The protective role of brown adipose tissue in cardiac cell damage after myocardial infarction and heart failure

The protective role of brown adipose tissue in cardiac cell damage after myocardial infarction and heart failure

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