Correction to: The elevated levels of urinary angiotensinogen are correlated with the severity of idiopathic membranous nephropathy

Tang, Ziyong; Wang, Yue; Tao, Liyuan; Guo, Yanhong; Zheng, Yimu; Zheng, Deyi

doi:10.1186/s12882-019-1229-x

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“…Idiopathic membranous nephropathy (IMN) is an autoimmune disease which is the most common type of nephrotic syndrome in the world for adults. [ 1 – 4 ] More than 75% of membranous nephropathy cases are suffering from IMN. [ 5 ] IMN involves functional damage of glomerular capillary wall characterized by the deposition of immune complexes and complement activation on the sub-epithelial space between glomerular basement membrane and the glomerular podocytes.…”

Section: Introductionmentioning

confidence: 99%

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Chinese medicinal herbs for idiopathic membranous nephropathy in adults with nephrotic syndrome

et al. 2021

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To assess the benefits and harms of Chinese medicinal herbs formulae for the treatment of idiopathic membranous nephropathy in adult patients with primary nephrotic syndrome. Only randomized controlled trials were included. We searched the Cochrane Central Register of Controlled Trials database, PubMed, EMBASE, Chinese National Knowledge Internet, Chinese Biomedicine Database, and VIP. All studies were analyzed using the criteria of the Cochrane Handbook and were assessed in terms of quality and the risk of bias. Review Manager ver. 5.3.5 software was used for the data analysis, and GRADE profiler software was employed to evaluate quality. Two studies were included (n = 126 Chinese participants). We found that compared with against conventional treatment, one Chinese medicinal herbs formula plus conventional treatment reduced 24-hours urinary total protein (mean differences –3.16 g/24 h, 95% confidence intervals –4.03 to –2.29), and two Chinese medicinal herbs formulae increased serum albumin levels (mean differences 3.18 g/L, 95% confidence intervals 1.12 to 5.52; I 2 = 0%). Chinese medicinal herbs formulae may reduce 24-hours urinary total protein and increase serum levels of albumin. However, larger and multicenter studies with high methodological quality are still needed.

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Section: Introductionmentioning

confidence: 99%

“…Idiopathic membranous nephropathy (IMN) is an autoimmune disease which is the most common type of nephrotic syndrome in the world for adults [1–4] . More than 75% of membranous nephropathy cases are suffering from IMN [5] .…”

Section: Introductionmentioning

confidence: 99%