Correlates of Chronic Kidney Disease in India

M, Roy

doi:10.1007/s42399-020-00538-z

Cited by 2 publications

(1 citation statement)

References 31 publications

(29 reference statements)

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“…Additionally, comprehensive investigations reported an increment in in-hospital mortality through cardiac rhythmia on COVID-19 patients. [108] Unfortunately, the type and severity of arrhythmias associated with COVID-19 have not been precisely described to date. [109] Nevertheless, sinus bradycardia with high-grade atrioventricular block, premature atrial beats, paroxysmal atrial fibrillation, and decreased left ventricular ejection fraction have been reported in COVID-19.…”

Section: Drug-induced Cardiovascular Injurymentioning

confidence: 99%

Drug‐induced organ injury in coronavirus disease 2019 pharmacotherapy: Mechanisms and challenges in differential diagnosis and potential protective strategies

Ommati

Mobasheri

Heidari

2021

J Biochem & Molecular Tox

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The world is currently facing an unprecedented pandemic caused by a newly recognized and highly pathogenic coronavirus disease 2019 (COVID‐19; induced by SARS‐CoV‐2 virus), which is a severe and ongoing threat to global public health. Since COVID‐19 was officially declared a pandemic by the World Health Organization in March 2020, several drug regimens have rapidly undergone clinical trials for the management of COVID‐19. However, one of the major issues is drug‐induced organ injury, which is a prominent clinical challenge. Unfortunately, most drugs used against COVID‐19 are associated with adverse effects in different organs, such as the kidney, heart, and liver. These side effects are dangerous and, in some cases, they can be lethal. More importantly, organ injury is also a clinical manifestation of COVID‐19 infection. These adverse reactions are increasingly recognized as outcomes of COVID‐19 infection. Therefore, the differential diagnosis of drug‐induced adverse effects from COVID‐19‐induced organ injury is a clinical complication. This review highlights the importance of drug‐induced organ injury, its known mechanisms, and the potential therapeutic strategies in COVID‐19 pharmacotherapy. We review the potential strategies for the differential diagnosis of drug‐induced organ injury. This information can facilitate the development of therapeutic strategies, not only against COVID‐19 but also for future outbreaks of other emerging infectious diseases.

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Section: Drug-induced Cardiovascular Injurymentioning

confidence: 99%