2024
DOI: 10.3897/folmed.66.e117367
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Correlating the genetic alterations and expression profile of the TRA2B gene in HNSCC and LUSC

Amba Esakki,
Anitha Pandi,
Smiline A S Girija
et al.

Abstract: Introduction: Transformer (TRA2B) is a serine/arginine-rich (SR)-like protein family that regulates the alternative splicing of several genes in a concentration-dependent manner. Amplification of the TRA2B gene, which codes for TRA2B, occurs in several malignancies, including those of the lung, cervix, head and neck, ovary, stomach, and uterine. Materials and methods: The present study design follows a computational approach to predict the molecular mechanisms underlying TRA2B alterations in two canc… Show more

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