Correlation between 18F-FDG dosage and SNR on various BMI patient groups tested in NEMA IEC PET phantom

Waeleh, Nazreen; Saripan, M. Iqbal; Musarudin, Marianie; Mashohor, Syamsiah; Saad, Fathinul Fikri Ahmad

doi:10.1016/j.apradiso.2021.109885

Cited by 2 publications

(2 citation statements)

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“…After filling in all the values in the Table (1) about mean, standard deviation, SNR, injection dose (in mci), weight (in kg), height (in m) and BMI, several figures related to BMI and SNR were made to see which the results were. All the figures were made with the values of the PET to see if there are any significant differences between them.…”

Section: Obesementioning

confidence: 99%

“…Worldwide, cancer ranks as the second largest cause of mortality among humans, caused by unhealthy lifestyles and lack of physical activity. Late disease identification is one of the causes contributing to such a high mortality rate [1,2]. Therefore, early identification is critical because it is the single most important factor in increasing a patient's chances of survival [3].…”

Section: Introductionmentioning

confidence: 99%

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Evaluation of the Influence of Body Mass Index and Signal-to-Noise Ratio on the PET/CT Image Quality in Iraqi Patients with Liver Cancer

Hade,

Essa

2023

East Eur. J. Phys.

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Image quality has been estimated and predicted using the signal to noise ratio (SNR). The purpose of this study is to investigate the relationships between body mass index (BMI) and SNR measurements in PET imaging using patient studies with liver cancer. Three groups of 59 patients (24 males and 35 females) were divided according to BMI. After intravenous injection of 0.1 mCi of 18F-FDG per kilogram of body weight, PET emission scans were acquired for (1, 1.5, and 3) min/bed position according to the weight of patient. Because liver is an organ of homogenous metabolism, five region of interest (ROI) were made at the same location, five successive slices of the PET/CT scans to determine the mean uptake (signal) values and its standard deviation. We obtained the liver's Signal-to-Noise Ratio from the ratio of both. Weight, height, SNR, and Body Mass Index were determined using a spreadsheet, and graphs were created to show the relationship between these variables. The graphs demonstrated that SNR decreases when BMI increases and that, despite an increase in injection dose, SNR also decreases. This is because heavier individuals take higher doses and, according to reports, have lower SNR. These results show that, despite receiving larger FDG doses, heavier patients' images, as measured by SNR, are of lower quality than thinner patients' images.

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Section: Obesementioning

confidence: 99%